LEUKOGRAM AND NEUTROPHIL OXIDATIVE METABOLISM OF DOGS WITH VISCERAL LEISHMANIASIS BEFORE AND AFTER TREATMENT WITH MEGLUMINE ANTIMONIATE AND ALLOPURINOL
DOI:
https://doi.org/10.5216/cab.v11i2.2149Keywords:
Animal SanityAbstract
Leukogram and neutrophil oxidative metabolism from dogs with visceral leishmaniasis (VL) were compared before and after treatment with meglumine antimoniate (AM) and with an association of meglumine antimoniate and allopurinol (AMA). The results obtained demonstrated that neutrophils of dogs with VL do not lose their capacity of reducing NBT and that oxidative metabolism has been more active in the majority of the cases. After treatment with AM and AMA, dogs with VL presented a redution of neutrophils oxidative metabolism, suggesting that this decrease was related with the decrease in the number of parasites and a probable inhibitor effect of these drugs on neutrophils oxidative metabolism.KEYWORDS: Glucantime, Leishmania sp, nitroblue tetrazolium (NBT), neutrophil functions.
Downloads
Download data is not yet available.
Published
2010-06-23
How to Cite
CIARLINI, P. C.; VALADARES, T. C.; IKEDA-GARCIA, F. A.; MARCONDES, M.; DE LIMA, V. M. F. LEUKOGRAM AND NEUTROPHIL OXIDATIVE METABOLISM OF DOGS WITH VISCERAL LEISHMANIASIS BEFORE AND AFTER TREATMENT WITH MEGLUMINE ANTIMONIATE AND ALLOPURINOL. Brazilian Animal Science/ Ciência Animal Brasileira, Goiânia, v. 11, n. 2, p. 369–375, 2010. DOI: 10.5216/cab.v11i2.2149. Disponível em: https://revistas.ufg.br/vet/article/view/2149. Acesso em: 24 nov. 2024.
Issue
Section
Veterinary Medicine
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g. in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
