EFFECTS OF FLUNIXIN MEGLUMINE CONJUNCTIVAL SHOT OVER THE HUMOR AQUEOUS PROTEIN OF DOGS SUBMITTED TO THE PARACENTESIS OF THE ANTERIOR CHAMBER

Authors

  • Paula Diniz Galera UnB
  • José Luiz Laus FCAV - UNESP - Jaboticabal
  • Ana Maria Barros Soares Universidade Federal Fluminense
  • Cassio Ricardo Ribeiro Universidade de Brasilia
  • Francislette Rodrigues de Melo União Pioneira de Integração Social

DOI:

https://doi.org/10.5216/cab.v10i4.5585

Keywords:

Animal Sanity

Abstract

Flunixin meglumine effects, over aqueous humor proteins of eyes on dogs who were submitted to paracentesis of the anterior chamber, were evaluated. To ten adult dogs clinically healthy were given a subconjunctival shot with flunixin meglumine (1.1mg/Kg) on the right eye and sterilized saline solution 0.9% on the left eye, with the same volume. After general anesthesia, were submitted to two paracentesis of the both eyes to collect 0.2mL of first and second aqueous. The samples were submitted to Bradford test, wich proteins concentrations were  15.98mg/dL ± 4.48 e 11.46mg/dL ± 2.72 for the right and the left eyes, respectively, on the first paracentesis and 119.8mg/dL ± 6.74 e 120.63mg/dL ± 22.4 for the right and the left eyes, on the second paracentesis. There was no significant statistically differences between the protein values of the treated eyes in comparison with the control one. When compared, the proteins concentrations between the first and second paracentesis of the right and left eyes, statistic differences were found between these two moments (p<0.001). SDS-PAGE showed differences in the protein patterns of aqueous humor in result of the paracentesis.
KEY WORDS: Aqueous humor, eye, flunixin meglumine, paracentesis, proteíns.

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Author Biographies

Paula Diniz Galera, UnB

MV, MSc, PhD. Professor Adjunto III - Cirurgia de Pequenos Animais - Faculdade de Agronomia e Medicina Veterinária da Universidade de Brasília

José Luiz Laus, FCAV - UNESP - Jaboticabal

MV, MSc, PhD. Professor Titular - Depto. Clinica e Cirurgia Veterinaria - Faculdade de Ciencias Agrarias e Veterinarias - UNESP - Jaboticabal

Ana Maria Barros Soares, Universidade Federal Fluminense

MV, MSc, PhD. Professora Adjunta - Depto. de Clínica Médica de Pequenos Animais - Faculdade de Veterinária - UFF

Cassio Ricardo Ribeiro, Universidade de Brasilia

MV, MSc, PhD.  Pos-doutorando do Instituto de Ciências Biológicas da Universidade de Brasilia

Francislette Rodrigues de Melo, União Pioneira de Integração Social

Bióloga. MSc. PhD em Bioquímica. Professor do Curso de Agronomia e Medicina Veterinária da UPIS.

Published

2009-12-20

How to Cite

GALERA, P. D.; LAUS, J. L.; SOARES, A. M. B.; RIBEIRO, C. R.; DE MELO, F. R. EFFECTS OF FLUNIXIN MEGLUMINE CONJUNCTIVAL SHOT OVER THE HUMOR AQUEOUS PROTEIN OF DOGS SUBMITTED TO THE PARACENTESIS OF THE ANTERIOR CHAMBER. Brazilian Animal Science/ Ciência Animal Brasileira, Goiânia, v. 10, n. 4, p. 1310–1316, 2009. DOI: 10.5216/cab.v10i4.5585. Disponível em: https://revistas.ufg.br/vet/article/view/5585. Acesso em: 4 nov. 2024.

Issue

Section

Veterinary Medicine

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