Metabolic markers and milk production by Holstein cows undergoing different protocols with cyanocobalamin and butaphosphan postpartum
DOI:
https://doi.org/10.1590/1809-6891v25e-77140EAbstract
The objective of this study was to evaluate the effects of different protocols combining
cyanocobalamin and butaphosphan on metabolic markers and milk production by Holstein cows
postpartum. We used 154 multiparous cows housed in a free-stall system and divided into five groups,
using the number of lactations and the probable date of calving as randomization criteria. The animals
received intramuscular applications of a 100 mg/mL butaphosphan and 0.05 mg/mL cyanocobalamin
combination. The treatment was delivered in a volume of 1 mL for every 20 Kg of body weight on
varying treatment days as follows: treatment 1 (T1), on delivery day (day 0) (n=36); T2, days 0 and 3 (n =
31); T3: days 0 and 7 (n = 30); T4: days 0, 3 and 7 (n = 28). The control group (CG) received saline solution
on days 0, 3 and 7 (n = 29). Blood samples were collected for metabolite evaluation on days 0, 7, 21 and
30. Milk production was recorded once a week for up to 98 lactation days. T4 elicited higher average
milk production (25.87±0.34 kg/day; P < 0.001) than all other groups. Administering butaphosphan and
cyanocobalamin on days 0, 3 and 7 postpartum increased milk production and improved energy and
liver metabolism in the animals.
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