Proteínas de fase aguda em coelhos submetidos à colecistectomia laparoscópica – LigaSure versus eletrocirúrgico

Autores

DOI:

https://doi.org/10.1590/1809-6891v25e-79416E

Resumo

Estudos demonstram que o dispositivo selante de vasos DSV-LigaSure promove menor dano tecidual que o eletrocirúrgico bipolar e o aumento e diminuição das concentrações de proteínas e imunoglobulinas após a colecistectomia laparoscópica é esperado e transitório. Objetivou-se comparar os valores séricos das proteínas de fase aguda e imunoglobulinas de coelhos submetidos à dissecção da vesícula biliar utilizando eletrocirúrgico bipolar (pinça Maryland) e DSV-LigaSure para determinar qual dos dissectores apresentou menor alteração inflamatória. Vinte coelhos foram distribuídos em dois grupos com dez animais cada, sendo o Grupo 1 submetido à técnica de colecistectomia laparoscópica utilizando o eletrocirúrgico bipolar para dissecção e DSV-LigaSure para selar o ducto cístico e o Grupo 2, submetido à dissecção da vesícula biliar e selagem do ducto cístico utilizando o DSV- igaSure. As proteínas de fase aguda e imunoglobulinas foram avaliadas nos dias três, sete e 15 do período pós-
-operatório. As concentrações séricas de fibrinogênio, transferrina, IgG, α1- glicoproteína ácida, PM 23000 Da e proteína C reativa não apresentaram diferenças significativas entre os grupos, apenas diferenças significativas entre os dias de avaliação no mesmo grupo. IgA, ceruloplasmina e haptoglobina não apresentaram diferenças estatísticas entre grupos e nem entre dias de avaliação. Apenas albumina apresentou diferença entre grupos, onde o Grupo 1 demonstrou menor concentração da proteína após 15 dias. Ambos dissectores apresentaram alterações nas proteínas de fase aguda, demonstrando que não houve superioridade na técnica utilizando o DSV-LigaSure.

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Publicado

2024-09-24

Como Citar

MACHADO, A. C. S.; WITTMAACK, M. C. N.; VERA, M. C. M.; SILVA, D. G. da; SEMBENELLI, G.; MONTANHIM, G. L.; IDO, C. K.; RIBEIRO, J. de O.; MENEZES, M. P. de; MORAES , P. C. Proteínas de fase aguda em coelhos submetidos à colecistectomia laparoscópica – LigaSure versus eletrocirúrgico. Ciência Animal Brasileira / Brazilian Animal Science, Goiânia, v. 25, 2024. DOI: 10.1590/1809-6891v25e-79416E. Disponível em: https://revistas.ufg.br/vet/article/view/79416. Acesso em: 21 dez. 2024.

Edição

Seção

MEDICINA VETERINÁRIA