The effect of plectasin supplementation on small intestines morphometric characteristics, blood profile, and growth performance of broiler chickens

Albert Sean S. Favorito; Michelle Grace V. Paraso; Arville Mar Gregorio A. Pajas; Joseph F. dela Cruz

doi:10.1590/1809-6891v26e-80624E

Autores

Albert Sean S. Favorito University of the Philippines Los Baños, Los Baños, Laguna, Philippines https://orcid.org/0009-0001-2949-3051
Michelle Grace V. Paraso University of the Philippines Los Baños, Los Baños, Laguna, Philippines https://orcid.org/0000-0002-5079-3710
Arville Mar Gregorio A. Pajas University of the Philippines Los Baños, Los Baños, Laguna, Philippines https://orcid.org/0000-0003-0355-9371
Joseph F. dela Cruz University of the Philippines Los Baños, Los Baños, Laguna, Philippines https://orcid.org/0000-0002-2482-8019

DOI:

https://doi.org/10.1590/1809-6891v26e-80624E

Resumo

Peptídeos antimicrobianos, como a plectasina, foram propostos como substitutos adequados para antibióticos promotores de crescimento em animais de produção. Entretanto, sua eficácia nas condições locais das Filipinas ainda não foi determinada. Este estudo foi conduzido para avaliar a eficácia da plectasina no desempenho do crescimento, nas características morfométricas do intestino delgado e em parâmetros sanguíneos de frangos de corte. Trezentos frangos de corte da linhagem Ross de um dia de idade foram alocados aleatoriamente utilizando um delineamento em blocos completos casualizados, tendo o peso inicial como fator de bloqueio, nos seguintes grupos de tratamento: controle negativo (T1); 250 ppm de enramicina ou controle positivo (T2); 150 ppm de plectasina (T3); 300 ppm de plectasina (T4); e 450 ppm de plectasina (T5). A suplementação de plectasina a 150 ppm durante a fase de terminação melhorou o desempenho de crescimento dos frangos de corte (P<0,05), aumentando a taxa de conversão alimentar em 1,89±0,12 e aumentando o ganho médio diário (80,68±5,40g). O consumo médio diário de ração de todos os grupos de tratamento foi comparável durante todas as fases de alimentação. No entanto, a suplementação não afetou as medidas morfométricas do intestino delgado e os níveis séricos de glicose, triglicerídeos e colesterol. Esse estudo indica que o peptídeo antimicrobiano plectasina tem efeitos benéficos sobre o desempenho do crescimento e melhora a eficiência da utilização de nutrientes sem interromper as funções fisiológicas normais.
Palavras-chave: plectasina; perfil sanguíneo; desempenho; morfologia intestinal; frangos de corte.

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