MACROSCOPIC, MORPHOLOGIC AND MORPHOMETRIC ASPECTS OF THE SPLEEN OF RATS AFTER TOTAL CLAMPING OF THE HEPATIC PEDICLE

Authors

  • Silvio Henrique Freitas Universidade de Cuiabá (UNIC), Cuiabá, Mato Grosso, Brasil
  • Joaquim Evêncio-Neto Universidade Federal Rural de Pernambuco (UFRPE), Recife, Pernambuco, Brasil
  • Renato Gebara Sampaio Dória Universidade de Cuiabá (UNIC), Cuiabá, Mato Grosso, Brasil
  • Fabio Souza Mendonça Universidade de Cuiabá (UNIC), Cuiabá, Mato Grosso, Brasil
  • Manuel Jesus Simões Universidade Federal de São Paulo
  • Lázaro Manoel Camargo Universidade de Cuiabá (UNIC), Cuiabá, Mato Grosso, Brasil
  • Abrão Antonio Sébe Universidade de Cuiabá (UNIC), Cuiabá, Mato Grosso, Brasil

Keywords:

Animal pathology

Abstract

One of the complications of hepatic pedicle total clamping is the splanchnic congestion and consequently a splenic congestion. The aim of this study was to observe the macro and microscopic alterations that occurred in the spleen during an ischemia produced by the hepatic pedicle clamping. Fourth male rats were divided in four groups of ten animals each. The control group (C) was not submitted to ischemia and the experimental groups (E1, E2 and E3) were submitted to the total clamping during 10, 20 and 30 minutes, respectively. After these periods, spleen fragments were collected and histological analyzed by the eosin-hematoxilin and ferric ferrocyanide staining technique. The results showed microscopic alterations at the E1, E2 and E3    groups that permitted to conclude that the total clamping of the hepatic pedicle promote intense vascular congestion, increase of the hemosiderin granules, decrease of the white pulp and increase of the red pulp, being these alterations more pronounced at the 30 minutes.
KEY WORDS: Congestion, hemossiderina, spleen, rats.

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Published

2009-12-17

How to Cite

FREITAS, S. H.; EVÊNCIO-NETO, J.; DÓRIA, R. G. S.; MENDONÇA, F. S.; SIMÕES, M. J.; CAMARGO, L. M.; SÉBE, A. A. MACROSCOPIC, MORPHOLOGIC AND MORPHOMETRIC ASPECTS OF THE SPLEEN OF RATS AFTER TOTAL CLAMPING OF THE HEPATIC PEDICLE. Brazilian Animal Science/ Ciência Animal Brasileira, Goiânia, v. 10, n. 4, p. 1216–1224, 2009. Disponível em: https://revistas.ufg.br/vet/article/view/2452. Acesso em: 13 apr. 2025.

Issue

Vol. 10 No. 4 (2009)

Section

Veterinary Medicine

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Copyright (c) 2009 Brazilian Animal Science/ Ciência Animal Brasileira

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