CLINICAL AND LABORATORIAL ALTERATIONS AS INDICATORS FOR ANTI-HELMINTIC TREATMENT IN SHEEP EXPERIMENTALLY INFECTED WITH Haemonchus contortus

Authors

  • Bárbara Nascimento Lemos Hupp Universidade Federal do Espírito Santo, Alegre, Espírito Santo, Brasil, barbaralemos24@hotmail.com
  • Marcelle Temporim Novaes Universidade Federal do Espírito Santo, Alegre, Espírito Santo, Brasil, marcelle_temporim@hotmail.com http://orcid.org/0000-0001-9077-5827
  • Marcela Santos Sena Martins Universidade Federal do Espírito Santo, Alegre, Espírito Santo, Brasil, marcelasena2@hotmail.com
  • Adriano Conti Hupp Universidade Federal do Espírito Santo, Alegre, Espírito Santo, Brasil, adrianohupp@gmail.com
  • Leonardo Oliveira Trivilin Universidade Federal do Espírito Santo, Alegre, Espírito Santo, Brasil, leotrivilin@gmail.com
  • Isabella Vilhena Freire Martins Universidade Federal do Espírito Santo, Alegre, Espírito Santo, Brasil, ivfmartins@gmail.com

DOI:

https://doi.org/10.1590/cab19142928

Keywords:

Parasithology

Abstract

The intensity of anemia and hypoproteinemia are indicators of the seriousness of haemonchosis. The objective of this study was to verify the changes in weight, hematocrit, and plasma protein, as well as the parasite load, indicating the need for anthelmintic intervention in sheep experimentally infected with Haemonchus contortus. Fourteen crossbred Santa Inês male sheep were used, weighing 42.5 (± 7.5) kg, nematodes-free. The animals were divided into two groups of seven animals each. The group of infected animals received 10,000 H. contortus larvae each. All animals were monitored after 21, 28, 35, 42, 49, 56, 63, and 70 days post-infection and the following parameters were assessed: EPG, Famacha©, weight, total plasma proteins, and hematocrit. In the infected group, the EPG varied and peaked on the 42nd follow-up day. The hematocrit became significantly lower after the experimental infection. Famacha score© ranged from 1 to 2 and it was significantly higher at 21, 28, 35 and 42 days. No change was observed in plasma protein level and body weight in the control group. Infection with up to 10,000 larvae of H. contortus. and EPG up to 2500 did not significantly affect weight, hematocrit, and plasma protein of crossbred Santa Inês sheep with no need for anthelmintic intervention.
Keywords: control; parasitic load; small ruminants.

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Author Biographies

Bárbara Nascimento Lemos Hupp, Universidade Federal do Espírito Santo, Alegre, Espírito Santo, Brasil, barbaralemos24@hotmail.com

Marcelle Temporim Novaes, Universidade Federal do Espírito Santo, Alegre, Espírito Santo, Brasil, marcelle_temporim@hotmail.com

Marcela Santos Sena Martins, Universidade Federal do Espírito Santo, Alegre, Espírito Santo, Brasil, marcelasena2@hotmail.com

Adriano Conti Hupp, Universidade Federal do Espírito Santo, Alegre, Espírito Santo, Brasil, adrianohupp@gmail.com

Leonardo Oliveira Trivilin, Universidade Federal do Espírito Santo, Alegre, Espírito Santo, Brasil, leotrivilin@gmail.com

Isabella Vilhena Freire Martins, Universidade Federal do Espírito Santo, Alegre, Espírito Santo, Brasil, ivfmartins@gmail.com

Published

2018-04-10

How to Cite

NASCIMENTO LEMOS HUPP, B.; TEMPORIM NOVAES, M.; SANTOS SENA MARTINS, M.; CONTI HUPP, A.; OLIVEIRA TRIVILIN, L.; VILHENA FREIRE MARTINS, I. CLINICAL AND LABORATORIAL ALTERATIONS AS INDICATORS FOR ANTI-HELMINTIC TREATMENT IN SHEEP EXPERIMENTALLY INFECTED WITH Haemonchus contortus. Brazilian Animal Science/ Ciência Animal Brasileira, Goiânia, v. 19, p. 1–10, 2018. DOI: 10.1590/cab19142928. Disponível em: https://revistas.ufg.br/vet/article/view/e-42928. Acesso em: 1 jul. 2024.

Issue

Section

MEDICINA VETERINÁRIA