Efeito do gel de plasma rico em plaquetas na cicatrização de enxertos cutâneos em equinos

Aline Fabrine Bonfá; Roberto Harutomi Corrêa Nomura; Antonia Maria Binder do Prado; Andressa Batista da Silveira; Lilian Pamela Tapia Carreno Dornbusch; Peterson Triches Dornbusch

doi:10.1590/1089-6891v18e-32307

EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES

Authors

Aline Fabrine Bonfá Pontifícia Universidade Católica do Paraná (PUCPR), Curitiba, Paraná, Brasil
Roberto Harutomi Corrêa Nomura Universidade Federal do Paraná (UFPR), Curitiba, Paraná, Brasil
Antonia Maria Binder do Prado Pontifícia Universidade Católica do Paraná (PUCPR), Curitiba, Paraná, Brasil
Andressa Batista da Silveira Pontifícia Universidade Católica do Paraná (PUCPR), Curitiba, Paraná, Brasil
Lilian Pamela Tapia Carreno Dornbusch Universidade Federal do Paraná (UFPR), Curitiba, Paraná, Brasil
Peterson Triches Dornbusch Universidade Federal do Paraná (UFPR), Curitiba, Paraná, Brasil

DOI:

https://doi.org/10.1590/1089-6891v18e-32307

Keywords:

Animal Sanity

Abstract

The platelet-rich plasma (PRP) gel is an autologous platelet concentration in a small plasma volume with the potential to improve the integration of the grafts. Eight adult equines were used, performing skin grafts, with 2.5x2.5 centimeters, on both sides of the neck, in which one was the treatment side, using the PRP gel, and the other side was the control. The animals were assessed after the surgery on days 0, 7, 14, 21, and 28, by clinical, histological, morphometric, and culture analysis of the grafts. The clinical, morphological, and biological analysis of tissue grafts revealed no significant differences between the control group and the treatment group with PRP. Histologic evaluation revealed an increase in acute inflammation on day 7 and collagen concentration on day 14, resulting from the release of growth factors by the platelets present in the gel, which did not differ in further moments. According to the experimental conditions used in this study, we concluded there were no significant differences between the side treated with PRP and the control side in skin grafts in horses.
Keywords: autologous; growth factors; integration of graft; time of healing.

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Published

2017-07-31

How to Cite

BONFÁ, Aline Fabrine; NOMURA, Roberto Harutomi Corrêa; PRADO, Antonia Maria Binder do; SILVEIRA, Andressa Batista da; DORNBUSCH, Lilian Pamela Tapia Carreno; DORNBUSCH, Peterson Triches. EFFECT OF PLATELET-RICH PLASMA GEL ON GRAFT SKIN HEALING IN EQUINES. Brazilian Animal Science/ Ciência Animal Brasileira, Goiânia, v. 18, 2017. DOI: 10.1590/1089-6891v18e-32307. Disponível em: https://revistas.ufg.br/vet/article/view/e-32307. Acesso em: 14 dec. 2025.

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Issue

Vol. 18 (2017): Continuous publication

Section

VETERINARY MEDICINE

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