Biochemical parameters and assessment of passive immunity transfer in elite Santa Inês lambs born from single and twin births
DOI:
https://doi.org/10.1590/1809-6891v26e-81436EAbstract
Abstract: Colostrum intake within the first hours of life is essential for neonatal survival. Lambs born from twin pregnancies may experience failure in passive immunity transfer (PIT), which can affect the serum concentrations of several metabolites. This study aimed to evaluate serum biochemical constituents and PIT in Santa Inês lambs born from single (Sg; n=19) and twin (Tw; n=28) births. Blood samples were collected at 0, 24, 48, 72, and 96 hours after birth, and analyzed for total protein, albumin, globulin, urea, creatinine, cholesterol, triglycerides, calcium (Ca), phosphorus (P), magnesium (Mg), and the enzymatic activities of aspartate aminotransferase (AST) and gamma-glutamyltransferase (GGT). Lambs in the GS group showed higher birth weight (3.98 kg vs. 3.03 kg; p<0.05), total protein (6.12 g/dL vs. 5.32 g/dL), globulin (4.35 g/dL vs. 3.64 g/dL), and GGT (322.93 U/L vs. 543.90 U/L) at 24 hours post-partum. Considering the association between globulin and immunoglobulin levels, the data suggest partial PIT failure in twin-born lambs. Additionally, significant differences (p<0.05) were observed in the mean values of albumin (1.87 vs. 1.80 g/dL), P (7.92 vs. 7.24 mg/dL), and Mg (2.51 vs. 2.37 mg/dL), with higher levels in the GS group. The remaining parameters remained within the reference ranges for the species. It is concluded that lambs from twin pregnancies are at greater risk of PIT failure and present lower serum levels of constituents related to neonatal immunity and metabolism, highlighting the importance of assisted colostrum management in such cases.
Key-words: colostrum; liver enzymes; minerals; neonates; total protein.
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