ECHOCARDIOGRAPHIC ASSESSMENT AFTER INTRAVENOUS AMITRAZ OR XYLAZINE INJECTION IN CATS

Authors

  • Andre Escobar Faculdade de Ciências Agrárias e Veterinárias, UNESP de Jaboticabal
  • Gláucia Bueno Pereira Neto Faculdade de Ciências Agrárias e Veterinárias, UNESP de Jaboticabal
  • Paulo Aléscio Canola Faculdade de Ciências Agrárias e Veterinárias, UNESP de Jaboticabal
  • Marina Ceccato Mendes Faculdade de Ciências Agrárias e Veterinárias, UNESP de Jaboticabal
  • Aparecido Antônio Camacho Faculdade de Ciências Agrárias e Veterinárias, UNESP de Jaboticabal
  • Carlos Augusto Araújo Valadão Faculdade de Ciências Agrárias e Veterinárias, UNESP de Jaboticabal

DOI:

https://doi.org/10.5216/cab.v12i1.8092

Keywords:

Animal sanity

Abstract

Amitraz acts on a2-adrenergic receptors in a competitive and reversible way, leading to some xylazine-like effects. To evaluate the left ventricular function index after amitraz or xylazine administration, eight mongrel cats were submitted to intravenous injection: group X (xylazine), group A (amitraz) or group D (diluent). The same cats were used in all groups, after a 15-day interval. Heart rate (HR) and rhythm, shortening fraction (%SF), ejection fraction (%EF) and cardiac index (CI) were measured by echocardiography immediately before and during 60 minutes after drug injection. Amitraz and xylazine induced first-degree atrioventricular block (1st AVB) and decreases in HR, %SF, %EF and CI. The mean values of HR and all echocardiographic parameters of group X were significantly lower comparing to group A. It was concluded that both a2-agonists produce bradycardia and 1st AVB, but xylazine causes greater depression of the cardiac contractility.  

KEYWORDS: Amitraz, xylazine, echocardiography, electrocardiography, cats

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Published

2011-03-31

How to Cite

ESCOBAR, A.; PEREIRA NETO, G. B.; CANOLA, P. A.; MENDES, M. C.; CAMACHO, A. A.; VALADÃO, C. A. A. ECHOCARDIOGRAPHIC ASSESSMENT AFTER INTRAVENOUS AMITRAZ OR XYLAZINE INJECTION IN CATS. Brazilian Animal Science/ Ciência Animal Brasileira, Goiânia, v. 12, n. 1, p. 156–162, 2011. DOI: 10.5216/cab.v12i1.8092. Disponível em: https://revistas.ufg.br/vet/article/view/8092. Acesso em: 17 jul. 2024.

Issue

Vol. 12 No. 1 (2011)

Section

Veterinary Medicine

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