Avaliação ecocardiográfica de gatos após a administração intravenosa de amitraz ou xilazina

Andre Escobar; Gláucia Bueno Pereira Neto; Paulo Aléscio Canola; Marina Ceccato Mendes; Aparecido Antônio Camacho; Carlos Augusto Araújo Valadão

doi:10.5216/cab.v12i1.8092

ECHOCARDIOGRAPHIC ASSESSMENT AFTER INTRAVENOUS AMITRAZ OR XYLAZINE INJECTION IN CATS

Authors

Andre Escobar Universidade Estadual Paulista (UNESP), Jaboticabal, São Paulo, Brasil
Gláucia Bueno Pereira Neto Universidade Estadual Paulista (UNESP), Jaboticabal, São Paulo, Brasil
Paulo Aléscio Canola Universidade Estadual Paulista (UNESP), Jaboticabal, São Paulo, Brasil
Marina Ceccato Mendes Universidade Estadual Paulista (UNESP), Jaboticabal, São Paulo, Brasil
Aparecido Antônio Camacho Universidade Estadual Paulista (UNESP), Jaboticabal, São Paulo, Brasil
Carlos Augusto Araújo Valadão Universidade Estadual Paulista (UNESP), Jaboticabal, São Paulo, Brasil

DOI:

https://doi.org/10.5216/cab.v12i1.8092

Keywords:

Animal sanity

Abstract

Amitraz acts on a2-adrenergic receptors in a competitive and reversible way, leading to some xylazine-like effects. To evaluate the left ventricular function index after amitraz or xylazine administration, eight mongrel cats were submitted to intravenous injection: group X (xylazine), group A (amitraz) or group D (diluent). The same cats were used in all groups, after a 15-day interval. Heart rate (HR) and rhythm, shortening fraction (%SF), ejection fraction (%EF) and cardiac index (CI) were measured by echocardiography immediately before and during 60 minutes after drug injection. Amitraz and xylazine induced first-degree atrioventricular block (1st AVB) and decreases in HR, %SF, %EF and CI. The mean values of HR and all echocardiographic parameters of group X were significantly lower comparing to group A. It was concluded that both a2-agonists produce bradycardia and 1st AVB, but xylazine causes greater depression of the cardiac contractility.

KEYWORDS: Amitraz, xylazine, echocardiography, electrocardiography, cats

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Published

2011-03-31

How to Cite

ESCOBAR, Andre; NETO, Gláucia Bueno Pereira; CANOLA, Paulo Aléscio; MENDES, Marina Ceccato; CAMACHO, Aparecido Antônio; VALADÃO, Carlos Augusto Araújo. ECHOCARDIOGRAPHIC ASSESSMENT AFTER INTRAVENOUS AMITRAZ OR XYLAZINE INJECTION IN CATS. Brazilian Animal Science/ Ciência Animal Brasileira, Goiânia, v. 12, n. 1, p. 156–162, 2011. DOI: 10.5216/cab.v12i1.8092. Disponível em: https://revistas.ufg.br/vet/article/view/8092. Acesso em: 31 dec. 2025.

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Issue

Vol. 12 No. 1 (2011)

Section

Veterinary Medicine

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