Tetanus in a canine: clinical and therapeutic aspects
DOI:
https://doi.org/10.1590/1809-6891v24e-73825EAbstract
Tetanus is a serious and rare disease in small animals, of an acute nature and mediated by the action of the neurotoxin tetanospasmin, from the bacillus Clostridium tetani. This report describes a case of tetanus in a canine, with emphasis on its clinical and therapeutic aspects, in addition to its clinical recovery. A canine, female, Pitbull breed, five months old, in status epilepticus, was attended at the Veterinary Hospital of the University of Passo Fundo. After stabilizing the patient, the animal was found in a trestle position, with generalized spastic paralysis, risus sardonicus, trismus, erect tail and ears, and difficulty in expanding the thorax. The presumptive diagnosis of tetanus was established based on the anamnesis, clinical signs, and laboratory findings. The established supportive treatment included hydro electrolytic replacement, anti-tetanus serum, antibiotic therapy, analgesia, myorelaxant and anticonvulsant drugs. The patient's intensive management was carried out with urethral and gastroesophageal probing, changes of position every two hours, and reduction of environmental stimuli. Physiotherapy and acupuncture were also used to complement the treatment and accelerate recovery. The patient was discharged one month after the beginning of the treatment, presenting satisfactory evolution. In the present case, the clinical examination in association with the characteristic clinical signs of the disease, added to the detailed anamnesis, was essential for the presumptive diagnosis of tetanus. In addition, intensive management, drug treatment, physiotherapy, and acupuncture enabled the evolution of the clinical condition to cure.
Keywords: Clostridium tetani, diagnosis; spastic paralysis; tetanospasmin; treatment.
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Rossetto O, Pirazzini M, Montecucco C. Current gaps in basic science knowledge of botulinum neurotoxin biological actions. Toxicon. 2015;107:59-63. Doi: 10.1016/j.toxicon.2015.07.002
Popoff MR. Tetanus in animals. Journal of Veterinary Diagnostic Investigation. 2020;32(2):184-91. Doi: 10.1177/1040638720906814
Fawcett A, Irwin P. Diagnosis and treatment of generalized tetanus in dogs. In Practice. 2014;36(10):482-93. Doi: 10.1136/inp.g6312
Greene CE. Infecções Micobacterianas. In: C.E G, editor. Doenças Infecciosas em Cães e Gatos. 4. Rio de Janeiro Guanabara Koogan Ltda; 2015. p. 1068-122.
Bandt C, Rozanski EA, Steinberg T, Shaw SP. Retrospective study of tetanus in 20 dogs: 1988–2004. Journal of the American Animal Hospital Association. 2007;43(3):143-8. Doi: 10.5326/0430143
Taylor MA. Tetanus. Continuing Education In Anaesthesia Critical Care & Pain 3. Oxford University Press: Elsevier; 2006. p. 101-4.
Sims C, Waldron R, Marcellin-Little DJ. Rehabilitation and physical therapy for the neurologic veterinary patient. Veterinary Clinics: Small Animal Practice. 2015;45(1):123-43. Doi: 10.1016/j.cvsm.2014.09.007
Bianchi RM, Panziera W, Galiza GJNd, Kommers GD, Fighera RA. Rabies outbreak in buffaloes in Rio Grande do Sul, Brazil. Ciência Rural. 2017;47. Doi: 10.1590/0103-8478cr20160523
Linnenbrink T, McMichael M. Tetanus: pathophysiology, clinical signs, diagnosis, and update on new treatment modalities. Journal of Veterinary Emergency and Critical Care. 2006;16(3):199-207. Doi: 10.1111/j.1476-4431.2006.00192.x
Dürre P. Biobutanol: an attractive biofuel. Biotechnology Journal: Healthcare Nutrition Technology. 2007;2(12):1525-34. Doi: 10.1002/biot.200700168
Hassel B. Tetanus: pathophysiology, treatment, and the possibility of using botulinum toxin against tetanus-induced rigidity and spasms. Toxins (Basel). 2013;5(1):73-83. Doi: 10.3390/toxins5010073
Burkitt JM, Sturges BK, Jandrey KE, Kass PH. Risk factors associated with outcome in dogs with tetanus: 38 cases (1987–2005). Journal of the American Animal Hospital Association.. 2007;230(1):76-83. Doi: 10.2460/javma.230.1.76
Weiss G, Ganz T, Goodnough LT. Anemia of inflammation. Blood, The Journal of the American Society of Hematology. 2019;133(1):40-50. Doi: 10.1182/blood-2018-06-856500
Stockham SL, Scott MA. Leucócitos. In: Stockham SL, Scott MA, editors. Fundamentos de Patologia Clínica Veterinária. Rio de Janeiro: Guanabara Koogan; 2011. p. 45-89.
Tavares W. O Clostridium tetani e o tétano. Revista da Sociedade Brasileira de Medicina Tropical. 1973;7:57-68. Doi: 10.1590/S0037-86821973000100007
Canal I, Lopes F, Canal R. Tétano: também em animais de companhia. Revista Nosso Clínico. 2006;9:48-58.
Farrow B, Love D. Bacterial, viral and other infectious problems. In: Ettinger, SJ Textbook of veterinary internal medicine Diseases of the dog and cat. 1983;2:269-319.
Acke E, Jones BR, Breathnach R, McAllister H, Mooney CT. Tetanus in the dog: review and a case report of concurrent tetanus with hiatal hernia. Irish Veterinary Journal. 2004;57(10):1-5. Doi: 10.1186/2046-0481-57-10-593
Spinosa H, Górniak S, Bernardi M. Farmacologia Aplicada à Medicina Veterinária. Rio de Janeiro: Guanabara Koogan; 2017.
Farrar J. Neurological aspects of tropical disease tetanus. Journal of Neurology, Neurosurgery, and Psychiatry. 2000;69:292-301. Doi: 10.1136/jnnp.69.3.292
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