On the efficacy, innocuity and residual depletion of flavomycin in confined steers
DOI:
https://doi.org/10.1590/1809-6891v23e-72054EAbstract
Flavomycin is a non-ionophore additive little studied in finishing confined cattle. Therefore, this study aimed to evaluate the effectiveness of flavomycin on productive performance, ingestive behavior, carcass traits and biochemical parameters of steers finished in confinement. 32 whole steers, ½ Angus e ½ Nellore blood, from the same herd, with a mean age of 11 ± 1.5 months and initial body weight of 337 ± 6 kg were evaluated. The experiment was a randomized block design, consisting of two treatments and eight replications, as follows: Diet without flavomycin (control) and Diet with flavomycin (0.5 g FLAVIMPEX®80 animal day-1). There was no difference between treatments, the average dry matter intake of the animals was 10.03 kg day-1, feed efficiency was 0.158 kg, average daily gain was 1.593 kg day-1, apparent diet digestibility was 61.69%. The use of flavomycin was not effective in animal performance, and caused no changes in ingestive behavior and carcass traits of the animals. Total Plasma Protein, Aspartate amino-transferase and creatinine were lower for animals supplemented with flavomycin compared to the control group. In relation to the experimental period, there was a reduction in the levels of Total Plasma Protein, an increase in albumin, Gamma-Glutamyl Transferase and urea in cattle, but all remained within the reference range for the species.
Keywords: Animal performance; Biochemical markers; Food additive; Ingestive behavior.
Downloads
References
Ramos MM, Berber RCA, Moreira PSA. (2019). Productive performance of Nellore steers in pasture with association of flavomycin and monensin. Sci Elect Arch. 2019; 12(2): 54-58.
Schären M, Drong C, Kiri K, Riede S, Gardener M, Meyer U, Hummel J, Urich T, Breves G, Dänicke S. Differential effects of monensin and a blend of essential oils on rumen microbiota composition of transition dairy cows. J Dairy Sci. 2017;100: 2765–2783. https://doi.org/10.3168/jds.2016-11994.
Limede AC, Marques RS, Polizel DM, Cappellozza BI, Miszura AA, Barroso JPR, Martins AS, Sardinha LA, Baggio M, Pires AV. Effects of supplementation with narasin, salinomycin, or flavomycin on performance and ruminal fermentation characteristics of Bos indicus Nellore cattle fed with forage-based diets. J Anim Sci. 2021; 99(4):1-11. https://doi.org/10.1093/jas/skab005.
Galligan D. Evaluating the cost effectiveness of feed additives. WCDS Advances in Dairy, Technology. 29nd ed; 2017. p. 147-158.
Tae-Il K, Dong-Hyun L, Sun-Sik J, Sang-Bum K, Seong-Min P, Ji-Hoo P, Kwang-Seok K, Vijayakumar M. Effects of supplementing Barodon, Bacillus subtilis, and Ampbio on growth performance, biochemical metabolites, and hormone levels in Korean native heifers. Trop Anim Health Prod. 2018;50(7): 1637-1643. https://doi.org/10.1007/s11250-018-1606-7.
Volke F, Waschipky R, Pampel A, Donnerstag A, Lantzsch G, Pfeiffer H, Richter W, Klose G, Welzel P. Characterisation of antibiotic moenomycin A interaction with phospholipid model membranes. Chem. Phys. Lipids. 1997;85(2):115–123. https://doi.org/10.1016/s0009-3084(96)02649-7.
Edwards JE, MCewan NR, Mckain N, Walker N, Wallace RJ. Influence of flavomycin on ruminal fermentation and microbial populations in sheep. Microbiology. 2005a;151(3):717-725. https://doi.org/10.1099/mic.0.27602-0.
Edrington TS, Callaway TR, Varey PD, Jung YS, Bischoff KM, Elder RO, Anderson RC, Kutter E, Brabban AD, Nisbet DJ. Effects of the antibiotic ionophores monensin, lasalocid, laidlomycin propionate and bambermycin on Salmonella and E. coli O157:H7 in vitro. J. Appl. Microbiol. 2003;94(2):207–213. https://doi.org/10.1046/j.1365-2672.2003.01822.x.
Edwards JR, Bequette BJ, Mckain N, Mcewan NR, Wallace RJ. Influence of flavomycin on microbial numbers, microbial metabolism and gut tissue protein turnover in the digestive tract of sheep. Br J Nutr. 2005b;94(1):64-70. https://doi.org/10.1079/BJN20051444.
Association of Official Analytical Chemists. Official methods of analysis. 16nd ed. Washington, DC, 1995.
Van Soest, PJ, Robertson, JB, Lewis, BA. Symposium: carbohydrate methodology, metabolism, and nutritional implications in dairy cattle. J Dairy Sci. 1991;74(10):3583-3597. https://doi.org/10.3168/jds.S0022-0302(91)78551-2.
Goering, HK, Van Soest, PJ. Forage fiber analysis: device reagents, procedures and some applications. Washington: DC, 1970.
Silva DJ, Queiroz AC. Análise de Alimentos, métodos químicos e biológicos. 3 ed; 2009.
Bolsen, KK, Ashbell, G, Weinberg, ZG. Silage fermentation and silage additives-Review. J Anim Sci. 1996;5(1): 483-494. https://doi.org/10.5713/ajas.1996.483.
Tedesco MJ, Gianello C, Bissani CA, Bohnen H, Volhweiss SJ. Análises de solo, plantas e outros materiais. 2 ed. Porto Alegre: Universidade Federal do Rio Grande do Sul; 1995. 173p.
Muller L. Normas para avaliação de carcaças e concurso de carcaça de novilhos. 2.ed. Santa Maria: Universidade Federal de Santa Maria; 1987. 31p.
Polizel DM, Cappellozza BI, Hoe F, Lopes CN, Barroso JP, Miszura A, Oliveira GB, Gobato L, Pires AV. Effects of narasin supplementation on dry matter intake and rumen fermentation characteristics of Bos indicus steers fed a high-forage diet. Transl Anim Sci. 2020;4(1):118–128. https://doi.org/10.1093/tas/txz164.
Lemos BJM, Castro FGF, Santos LS, Mendonça BPC, Couto VRM, Fernades JJR. Monensin, virginiamycin, and flavomycin in a no-roughage finishing diet fed to zebu cattle. J Anim Sci. 2016;94(1):4307–4314. https://doi.org/10.2527/jas2016-0504.
Cardoso EO, Silva RR, Silva RR, Carvalho GGP, Júnior GT, Souza SO, Lisboa MM, Pereira MMS, Mendes FBL, Almeida VVS, Oliveira AC. Influência do sexo no desempenho, característica de carcaça e viabilidade econômica de bovinos alimentados com dieta de alto grão. Semin Cienc Agrar. 2014;35(4Supl): 2643-2654. https://doi.org/10.5433/1679-0359.2014v35n4Suplp2643.
Kaneko JJ, Harvey JW, Bruss ML. Clinical biochemistry of domestic animals. 6st ed. Cambridge: Academic Press; 2008. 936p.
Neumann M, Ueno RK, Horst EH, Kowalski LH, Eto AK, Barcellos JOJ, Mizubuti IY. Production performance and safety of meat from beef cattle finished in feedlots using salinomycin in the diet. Semin Cienc Agrar. 2016;37(6):4221-4234. https://doi.org/10.5433/1679-0359.2016v37n6p4221.
Owens FN, Gill DR, Secrist DS, Coleman SW. Review of some aspects of growth and development of feedlot cattle. J Anim Sci. 1995;73(10):3152-3172. 23. Nagaraja TG, Chengappa MM. Liver abscesses in feedlot cattle: a review. J Anim Sci. 1998;76(1):287-298. https://doi.org/10.2527/1998.761287x.
Conceição WLF, Brito DRB, Rocha TG, Silva DGD, Chaves DP, Fagliari JJ. Perfil bioquímico sérico de vacas das raças nelore e girolando criadas no estado do maranhão. Ciênc. Anim Bras. 2019;20(1):1-7. https://doi.org/10.1590/1089-6891v20e-33796.
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Brazilian Animal Science/ Ciência Animal Brasileira
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g. in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
