PLASMATIC VARIATION OF VASOACTIVE AMINES IN HORSES UNDER EFFECT OF CARBOHYDRATE OVERLOAD AND NON-STEROIDAL ANTIINFLAMMATORIES

Authors

  • Renata Sampaio Costa Universidade Federal de Minas Gerais
  • Paulo de Tarso Botteon UFRJ
  • Vany Ferraz UFMG
  • Fabíola de O. Paes Leme UFMG
  • Rafael Resende Faleiros UFMG
  • Geraldo Eleno Silveira Alves UFMG

DOI:

https://doi.org/10.5216/cab.v13i1.6970

Keywords:

Animal Sanity

Abstract

Twenty horses were submitted to carbohydrate overload (CO) and plasmatic concentrations of the bioactive amine serotonin (5-HT), putrescin (PUT) and cadaverin (CAD) were determined by gas chromatography. After 36h of carbohydrate overloading, horses were randomly distributed into four groups (n=5) and were submitted to four intravenous treatments every 12 hours. The treatments were as follows: 10ml of saline (GC), ketoprofen 2.2mg/kg (GK), phenylbutazone 4.4mg/kg (GF), and flunixin meglumine 1.1mg/kg (GFM). Blood samples were collected at regular intervals (0-72h) after the CO. After 6h, there were peaks in the concentrations of 5-HT, which rapidly returned to values above the basal standard. No variations of PUT concentrations were observed; however CAD concentrations increased at 6h, remaining elevated (with some variation) until the end of the observation period. In conclusion, CO induced early (6h) increases in plasmatic concentrations of 5-HT and CAD. Plasmatic concentrations of the amines were not changed by any of the treatments used.

KEYWORDS: equine; NSAIDs; vasoactives amines.

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Published

2012-03-29

How to Cite

COSTA, R. S.; BOTTEON, P. de T.; FERRAZ, V.; PAES LEME, F. de O.; FALEIROS, R. R.; SILVEIRA ALVES, G. E. PLASMATIC VARIATION OF VASOACTIVE AMINES IN HORSES UNDER EFFECT OF CARBOHYDRATE OVERLOAD AND NON-STEROIDAL ANTIINFLAMMATORIES. Brazilian Animal Science/ Ciência Animal Brasileira, Goiânia, v. 13, n. 1, p. 93–98, 2012. DOI: 10.5216/cab.v13i1.6970. Disponível em: https://revistas.ufg.br/vet/article/view/6970. Acesso em: 13 may. 2024.

Issue

Vol. 13 No. 1 (2012)

Section

Veterinary Medicine

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