Variações plasmáticas de aminas vasoativas em equinos sob efeito de sobrecarga de carboidratos e anti-inflamatórios não esteroidais

Renata Sampaio Costa; Paulo de Tarso Botteon; Vany Ferraz; Fabíola de O. Paes Leme; Rafael Resende Faleiros; Geraldo Eleno Silveira Alves

doi:10.5216/cab.v13i1.6970

PLASMATIC VARIATION OF VASOACTIVE AMINES IN HORSES UNDER EFFECT OF CARBOHYDRATE OVERLOAD AND NON-STEROIDAL ANTIINFLAMMATORIES

Authors

Renata Sampaio Costa Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brasil
Paulo de Tarso Botteon Universidade Federal Rural do Rio de Janeiro, Seropédica, Rio de Janeiro, Brasil
Vany Ferraz Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brasil
Fabíola de O. Paes Leme Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brasil
Rafael Resende Faleiros Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brasil
Geraldo Eleno Silveira Alves Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brasil

DOI:

https://doi.org/10.5216/cab.v13i1.6970

Keywords:

Animal Sanity

Abstract

Twenty horses were submitted to carbohydrate overload (CO) and plasmatic concentrations of the bioactive amine serotonin (5-HT), putrescin (PUT) and cadaverin (CAD) were determined by gas chromatography. After 36h of carbohydrate overloading, horses were randomly distributed into four groups (n=5) and were submitted to four intravenous treatments every 12 hours. The treatments were as follows: 10ml of saline (GC), ketoprofen 2.2mg/kg (GK), phenylbutazone 4.4mg/kg (GF), and flunixin meglumine 1.1mg/kg (GFM). Blood samples were collected at regular intervals (0-72h) after the CO. After 6h, there were peaks in the concentrations of 5-HT, which rapidly returned to values above the basal standard. No variations of PUT concentrations were observed; however CAD concentrations increased at 6h, remaining elevated (with some variation) until the end of the observation period. In conclusion, CO induced early (6h) increases in plasmatic concentrations of 5-HT and CAD. Plasmatic concentrations of the amines were not changed by any of the treatments used.

KEYWORDS: equine; NSAIDs; vasoactives amines.

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Published

2012-03-29

How to Cite

COSTA, Renata Sampaio; BOTTEON, Paulo de Tarso; FERRAZ, Vany; LEME, Fabíola de O. Paes; FALEIROS, Rafael Resende; ALVES, Geraldo Eleno Silveira. PLASMATIC VARIATION OF VASOACTIVE AMINES IN HORSES UNDER EFFECT OF CARBOHYDRATE OVERLOAD AND NON-STEROIDAL ANTIINFLAMMATORIES. Brazilian Animal Science/ Ciência Animal Brasileira, Goiânia, v. 13, n. 1, p. 93–98, 2012. DOI: 10.5216/cab.v13i1.6970. Disponível em: https://revistas.ufg.br/vet/article/view/6970. Acesso em: 6 dec. 2025.

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Issue

Vol. 13 No. 1 (2012)

Section

Veterinary Medicine

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