IMMUNOGLOBULIN LEVELS IN Trypanosoma evansi INFECTED RATS

Authors

  • Lucas Trevisan Gressler Universidade Federal de Santa Maria (UFSM), Santa Maria, Rio Grande do Sul, Brasil
  • Aleksandro Schafer da Silva Universidade Federal de Santa Maria (UFSM), Santa Maria, Rio Grande do Sul, Brasil
  • Mateus Anderson Otto
  • Maria Isabel Azevedo
  • Régis Adriel Zanette Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brasil
  • Silvia Gonzalez Monteiro Universidade Federal de Santa Maria (UFSM), Santa Maria, Rio Grande do Sul, Brasil
  • Janio Morais Santurio Universidade Federal de Santa Maria (UFSM), Santa Maria, Rio Grande do Sul, Brasil

DOI:

https://doi.org/10.5216/cab.v11i1.5461

Keywords:

Animal Sanity

Abstract

This study aimed at evaluating the immunoglobulin levels in rats experimentally infected with Trypanosoma evansi. Twenty animals were inoculated with 106 trypomastigote forms and ten rats were used as control. Parasitemia was monitored by examining daily blood smears. Rats were separated into three equal groups in the fifth day PI: groups A and B were formed by rats with low and moderate parasitemia, respectively; group C was formed by non-infected rats. IgG and IgM were evaluated by ELISA test and were superior when compared to group C. The IgM levels did not differ between the infected groups. It may be concluded that the infected rats showed an immunological response against T. evansi, although this was not enough to eliminate the parasite in acute infection.

KEY WORDS: IgG, IgM, Ratus norvergicus, Trypanosoma evansi.

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Published

2010-04-01

How to Cite

GRESSLER, L. T.; SILVA, A. S. da; OTTO, M. A.; AZEVEDO, M. I.; ZANETTE, R. A.; MONTEIRO, S. G.; SANTURIO, J. M. IMMUNOGLOBULIN LEVELS IN Trypanosoma evansi INFECTED RATS. Brazilian Animal Science/ Ciência Animal Brasileira, Goiânia, v. 11, n. 1, p. 201–204, 2010. DOI: 10.5216/cab.v11i1.5461. Disponível em: https://revistas.ufg.br/vet/article/view/5461. Acesso em: 3 apr. 2025.

Issue

Vol. 11 No. 1 (2010)

Section

Veterinary Medicine

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Copyright (c) 2010 Brazilian Animal Science/ Ciência Animal Brasileira

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