PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE

Authors

Abstract

The use of opioids for analgesia is limited or undefined in ruminants. The aim of this study was to compare two analgesics opioids, morphine and tramadol, based on the clinical and pedometric evaluations of animals submitted to a temporary experimental arthritis and synovitis, developed at the distal interphalangeal joint after an intra-articular administration of amphotericin B. Six animals were used in two different treatments, using morphine, dose of 0,5 mg/kg, and twenty days later, tramadol, dose of 1,8 mg/kg, both intramuscularly. The animals were evaluated at 3-hour intervals for a total of 27 hours, observing the physiological parameters, ambulation and pedometer activity. Lameness and pedometer variations were observed in both treatments. Based on the variables of pedometric activity, a pattern of restlessness compatible with podal nociception was observed, and there was no interference of any of the drugs on lameness. It was concluded that morphine and tramadol, at the tested doses, were incapable of interfering in the lameness attenuation during the maximum painful stimulation moment in this experimental protocol of orthopedic pain.
Keywords: Amphotericin B; arthritis; lameness; pain; synovitis.

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Author Biographies

Geison Morel Nogueira, Faculdade de Medicina Veterinária, UFU, Uberlândia, MG, Brasil.

Faculdade de Medicina Veterinária - FAMEV

Sílvia Helena Venturoli Perri, Faculdade de Medicina Veterinária de Araçatuba, UNESP, Araçatuba, SP, Brasil.

Departamento de Apoio, Produção e Saúde Animal - DAPSA

Paulo Sérgio Patto Dos Santos, Faculdade de Medicina Veterinária de Araçatuba, UNESP, Araçatuba, SP, Brasil.

Departamento de Clínica, Cirurgia e Reprodução Animal - DCCRA

Celso Antonio Rodrigues, Faculdade de Medicina Veterinária e Zootecnia, UNESP, Botucatu, SP, Brasil.

Departamento de Cirurgia e Anestesiologia Veterinária - DCAV

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Published

2019-08-29

How to Cite

NOGUEIRA, G. M.; PERRI, S. H. V.; DOS SANTOS, P. S. P.; RODRIGUES, C. A. PEDOMETRY APPLIED TO A COMPARATIVE STUDY USING MORPHINE AND TRAMADOL IN BOVINE. Brazilian Animal Science/ Ciência Animal Brasileira, Goiânia, v. 20, p. 1–11, 2019. Disponível em: https://revistas.ufg.br/vet/article/view/44627. Acesso em: 22 nov. 2024.

Issue

Vol. 20 (2019): Continuous publication

Section

MEDICINA VETERINÁRIA

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