IMMUNOEXPRESSION OF MASPIN AND KI-67 AS PROGNOSTIC MARKERS FOR BENIGN CHARACTERIZATION OF A CANINE MAMMARY FIBROEPITHELIAL HYPERPLASIA: CASE REPORT
DOI:
https://doi.org/10.5216/cab.v11i4.3773Keywords:
Animal SanityAbstract
Mammary hyperplasia is characterized by an increase in the whole mammary gland, considered benign and with a good prognosis. A two-year-old dog showed a volume increase in the entire mammary chain after hormone stimulation. To characterize the process prognosis, a immunohistochemical procedure was used to evaluate the Maspin staining, considered good prognosis marker, and the Ki-67, a proliferation marker, whose high expression indicates malignancy. As a result, we obtained a low expression of Ki-67 and a high expression of Maspin, suggesting an excellent prognosis for the animal.Keywords: Female dog, imunohistochemistry, neoplasia, prognosis.
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Published
2010-12-21
How to Cite
ZUCCARI, D. A. P. de C.; CASTRO, R.; FRADE, C. S.; PIVARO, L. R.; CARMONA-RAPHE, J.; MAYER, Z. IMMUNOEXPRESSION OF MASPIN AND KI-67 AS PROGNOSTIC MARKERS FOR BENIGN CHARACTERIZATION OF A CANINE MAMMARY FIBROEPITHELIAL HYPERPLASIA: CASE REPORT. Brazilian Animal Science/ Ciência Animal Brasileira, Goiânia, v. 11, n. 4, p. 977–980, 2010. DOI: 10.5216/cab.v11i4.3773. Disponível em: https://revistas.ufg.br/vet/article/view/3773. Acesso em: 19 oct. 2024.
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Case report
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