Imunomarcação de leishmania sp. e aspectos histológicos na terceira pálpebra de cães naturalmente infectados por Leishmania (leishmania) chagasi.

Aline Maria Vasconcelos Lima; Adriana da Silva Santos; Mariana Batista Rodrigues Faleiro; Veridiana Maria Brianezi Dignani de Moura; Fábio Luiz da Cunha Brito; Luiz Augusto Batista Brito

doi:10.1590/1089-6891v16i426859

HYSTOPATHOLOGY AND Leishmania sp. IMMUNOSTAINING IN THIRD EYELID OF Leishmania (Leishmania) chagasi NATURALLY INFECTED DOGS

Authors

Aline Maria Vasconcelos Lima Universidade Federal de Goiás (UFG), Goiânia, Goiás, Brasil
Adriana da Silva Santos Instituto Federal Goiano (IFGoiano), Urutaí, Goiás, Brasil
Mariana Batista Rodrigues Faleiro Universidade Federal de Goiás (UFG), Goiânia, Goiás, Brasil
Veridiana Maria Brianezi Dignani de Moura Universidade Federal de Goiás (UFG), Goiânia, Goiás, Brasil
Fábio Luiz da Cunha Brito Instituto Qualittas de Pós-Graduação, Goiânia, Goiás, Brasil
Luiz Augusto Batista Brito Universidade Federal de Goiás (UFG), Goiânia, Goiás, Brasil

DOI:

https://doi.org/10.1590/1089-6891v16i426859

Keywords:

Histopathology

Abstract

Canine visceral leishmaniasis (CVL) is a disease with multisystemic injuries, and among the varioustissues affected, the third eyelid (TE) is often involved. This ocular adnexa has been studied for theleishmaniasis pathogenesis elucidation and for diagnosis advance. This study aimed to carry out theparasite immunodetection and evaluate histologic lesions in TE of Leishmania (leishmania) chagasinaturally infected dogs. Twenty-six TE samples from infected dogs were submitted to histologicevaluation and to immunohistochemistry for Leishmania sp. The main lesion observed in the thirdeyelid conjunctiva (TEC) was lymphoplasmacytic inflammation, with Mott cells and parasitizedhistiocytes. Additionally, loss of epithelial stratification, ulceration, goblet cells thinning or hyperplasiawere often found. The same inflammatory pattern was observed in the third eyelid lacrimal gland(TELG), often accompanied by acinar atrophy and secretory ducts dilatation. Immunohistochemistry revealed parasitism in all samples, in different intensities.

Keywords: canine visceral leishmaniasis; conjunctiva; dog; eye; lacrimal gland.

Downloads

Download data is not yet available.

Downloads

Published

2015-10-30

How to Cite

LIMA, Aline Maria Vasconcelos; SANTOS, Adriana da Silva; FALEIRO, Mariana Batista Rodrigues; MOURA, Veridiana Maria Brianezi Dignani de; BRITO, Fábio Luiz da Cunha; BRITO, Luiz Augusto Batista. HYSTOPATHOLOGY AND Leishmania sp. IMMUNOSTAINING IN THIRD EYELID OF Leishmania (Leishmania) chagasi NATURALLY INFECTED DOGS. Brazilian Animal Science/ Ciência Animal Brasileira, Goiânia, v. 16, n. 4, p. 538–547, 2015. DOI: 10.1590/1089-6891v16i426859. Disponível em: https://revistas.ufg.br/vet/article/view/26859. Acesso em: 22 dec. 2025.

Download Citation

Issue

Vol. 16 No. 4 (2015)

Section

Veterinary Medicine

License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g. in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).