HYSTOPATHOLOGY AND Leishmania sp. IMMUNOSTAINING IN THIRD EYELID OF Leishmania (Leishmania) chagasi NATURALLY INFECTED DOGS

Authors

  • Aline Maria Vasconcelos Lima Universidade Federal de Goiás; Escola de Veterinária e Zootecnia
  • Adriana da Silva Santos Instituto Federal Goiano Campus Urutaí
  • Mariana Batista Rodrigues Faleiro Universidade federal de Goiás
  • Veridiana Maria Brianezi Dignani de Moura Universidade Federal de Goiás; Escola de Veterinária e Zootecnia
  • Fábio Luiz da Cunha Brito VetVision Serviço de Oftalmologia Veterinária. Instituto Qualittas de Pós-graduação.
  • Luiz Augusto Batista Brito Universidade Federal de Goiás; Escola de Veterinária e Zootecnia

DOI:

https://doi.org/10.1590/cab.v16i4.26859

Keywords:

Histopathology

Abstract

Canine visceral leishmaniasis (CVL) is a disease with multisystemic injuries, and among the varioustissues affected, the third eyelid (TE) is often involved. This ocular adnexa has been studied for theleishmaniasis pathogenesis elucidation and for diagnosis advance. This study aimed to carry out theparasite immunodetection and evaluate histologic lesions in TE of Leishmania (leishmania) chagasinaturally infected dogs. Twenty-six TE samples from infected dogs were submitted to histologicevaluation and to immunohistochemistry for Leishmania sp. The main lesion observed in the thirdeyelid conjunctiva (TEC) was lymphoplasmacytic inflammation, with Mott cells and parasitizedhistiocytes. Additionally, loss of epithelial stratification, ulceration, goblet cells thinning or hyperplasiawere often found. The same inflammatory pattern was observed in the third eyelid lacrimal gland(TELG), often accompanied by acinar atrophy and secretory ducts dilatation. Immunohistochemistry revealed parasitism in all samples, in different intensities.

Keywords: canine visceral leishmaniasis; conjunctiva; dog; eye; lacrimal gland.

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Author Biographies

Aline Maria Vasconcelos Lima, Universidade Federal de Goiás; Escola de Veterinária e Zootecnia

Departamento de Medicina Veterinária.

Adriana da Silva Santos, Instituto Federal Goiano Campus Urutaí

Departamento de Medicina Veterinária.

Mariana Batista Rodrigues Faleiro, Universidade federal de Goiás

Doutoranda em Ciência Animal

Veridiana Maria Brianezi Dignani de Moura, Universidade Federal de Goiás; Escola de Veterinária e Zootecnia

Departamento de Medicina Veterinária.

Luiz Augusto Batista Brito, Universidade Federal de Goiás; Escola de Veterinária e Zootecnia

Departamento de Medicina Veterinária.

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Published

2015-10-30

How to Cite

LIMA, A. M. V.; SANTOS, A. da S.; FALEIRO, M. B. R.; MOURA, V. M. B. D. de; BRITO, F. L. da C.; BRITO, L. A. B. HYSTOPATHOLOGY AND Leishmania sp. IMMUNOSTAINING IN THIRD EYELID OF Leishmania (Leishmania) chagasi NATURALLY INFECTED DOGS. Brazilian Animal Science/ Ciência Animal Brasileira, Goiânia, v. 16, n. 4, p. 538–547, 2015. DOI: 10.1590/cab.v16i4.26859. Disponível em: https://revistas.ufg.br/vet/article/view/26859. Acesso em: 27 jul. 2024.

Issue

Vol. 16 No. 4 (2015)

Section

Veterinary Medicine

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