MACROSCOPIC, MORPHOLOGIC AND MORPHOMETRIC ASPECTS OF THE SPLEEN OF RATS AFTER TOTAL CLAMPING OF THE HEPATIC PEDICLE
DOI:
https://doi.org/10.5216/cab.v10i4.2452Keywords:
Animal pathologyAbstract
One of the complications of hepatic pedicle total clamping is the splanchnic congestion and consequently a splenic congestion. The aim of this study was to observe the macro and microscopic alterations that occurred in the spleen during an ischemia produced by the hepatic pedicle clamping. Fourth male rats were divided in four groups of ten animals each. The control group (C) was not submitted to ischemia and the experimental groups (E1, E2 and E3) were submitted to the total clamping during 10, 20 and 30 minutes, respectively. After these periods, spleen fragments were collected and histological analyzed by the eosin-hematoxilin and ferric ferrocyanide staining technique. The results showed microscopic alterations at the E1, E2 and E3 groups that permitted to conclude that the total clamping of the hepatic pedicle promote intense vascular congestion, increase of the hemosiderin granules, decrease of the white pulp and increase of the red pulp, being these alterations more pronounced at the 30 minutes.KEY WORDS: Congestion, hemossiderina, spleen, rats.
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Published
2009-12-17
How to Cite
FREITAS, S. H.; EVÊNCIO-NETO, J.; SAMPAIO DÓRIA, R. G.; SOUZA MENDONÇA, F.; SIMÕES, M. J.; CAMARGO, L. M.; SÉBE, A. A. MACROSCOPIC, MORPHOLOGIC AND MORPHOMETRIC ASPECTS OF THE SPLEEN OF RATS AFTER TOTAL CLAMPING OF THE HEPATIC PEDICLE. Brazilian Animal Science/ Ciência Animal Brasileira, Goiânia, v. 10, n. 4, p. 1216–1224, 2009. DOI: 10.5216/cab.v10i4.2452. Disponível em: https://revistas.ufg.br/vet/article/view/2452. Acesso em: 22 dec. 2024.
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Veterinary Medicine
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