HEMATOLOGICAL AND BIOCHEMICAL PROFILE OF SHEEP SUPPLEMENTED WITH SALINOMYCIN SUBMITTED TO EXPERIMENTAL LACTIC RUMINAL ACIDOSIS

Authors

  • Aerlem Cynnara Vieira Doutoranda UFRPE
  • Adaucides Câmara Câmara UFERSA
  • José A. Bastos Afonso Clínica de Bovinos de Garanhuns - UFRPE
  • Carla Lopes Mendonça Clínica de Bovinos de Garanhuns - UFRPE

DOI:

https://doi.org/10.5216/cab.v13i2.17263

Keywords:

Animal Sanity

Abstract

Twelve sheep were distributed into two groups, control (CG) and salinomycin (SG), to study clinical, hematological and biochemical alterations in sheep supplemented with the ionophore and to evaluate its effect in preventing experimental lactic ruminal acidosis which was induced with sucrose. Variables were analyzed at intervals of 4h, 8h, 12h, 16h, 24h, 32h and 48h post-induction (PI). The enzymes AST, GGT, ALP and CK were determined, and seric total protein (TP), albumin, urea, creatinine, blood count, total plasmatic protein (TPP), fibrinogen (PF), glucose and L-lactate were quantified. Clinical manifestations of lactic acidosis and lower ruminal pH values were observed 8h PI, with (P <0.05) in SG compared to the basal moment. Neutrophils showed higher scores (P <0.05) in CG compared to SG 4h PI. The PF reached significant values (P <0.05) in CG 48h PI compared to SG. Urea decreased (P <0.05) in both groups 12h PI. Glucose increased (P <0.05) when compared to CG at basal moment. There was a decrease (P <0.05) at urinary pH 12h up to 48h PI, compared to 0h time in CG, while the SG decreased (P <0.05) just at moments 12h and 16h PI. Salinomycin did not prevent acidosis, however, favored the reestablishment of the animals that received it.

KEYWORDS: clinical biochemistry; fermentation disturbance; ionophores; small ruminants.

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Author Biographies

Adaucides Câmara Câmara, UFERSA

Possui graduação em Medicina Veterinária pela Universidade Federal Rural do Semi Árido (2003) , especialização em Reprodução de Bovinos pela Universidade Federal Rural do Semi Árido (2006) e mestrado em Ciência Animal pela Universidade Federal Rural do Semi Árido (2008) .

José A. Bastos Afonso, Clínica de Bovinos de Garanhuns - UFRPE

Possui graduação em Medicina Veterinária pela Universidade Federal Rural de Pernambuco (1983), Mestrado em Medicina Veterinária pela Universidade Federal Rural do Rio de Janeiro (1991) e Doutorado em Medicina Veterinária pela Universidade Estadual Paulista Júlio de Mesquita Filho (1999). Atualmente é Médico Veterinário da Clínica de Bovinos, Campus Garanhuns da Universidade Federal Rural de Pernambuco. Tem experiência com ênfase em Clínica de Ruminantes, atuando principalmente na área de sanidade.

Carla Lopes Mendonça, Clínica de Bovinos de Garanhuns - UFRPE

Possui graduação em Medicina Veterinária pela Universidade Federal Rural do Rio de Janeiro (1988), Mestrado em Medicina Veterinária pela Universidade Federal Rural do Rio de Janeiro (1991) e Doutorado em Medicina Veterinária pela Universidade Estadual Paulista Júlio de Mesquita Filho (1999). Atualmente é Médica Veterinária da Clínica de Bovinos, Campus Garanhuns/UFRPE. Tem experiência na área de Medicina Veterinária, com ênfase em Sanidade de Ruminantes, atuando principalmente nos seguintes temas: Med. Vet. preventiva, Clínica de Ruminantes, Diagnóstico Laboratorial - Patologia Clínica Veterinária.

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Published

2012-06-27

How to Cite

VIEIRA, A. C.; CÂMARA, A. C.; BASTOS AFONSO, J. A.; MENDONÇA, C. L. HEMATOLOGICAL AND BIOCHEMICAL PROFILE OF SHEEP SUPPLEMENTED WITH SALINOMYCIN SUBMITTED TO EXPERIMENTAL LACTIC RUMINAL ACIDOSIS. Brazilian Animal Science/ Ciência Animal Brasileira, Goiânia, v. 13, n. 2, p. 259–271, 2012. DOI: 10.5216/cab.v13i2.17263. Disponível em: https://revistas.ufg.br/vet/article/view/17263. Acesso em: 13 may. 2024.

Issue

Vol. 13 No. 2 (2012)

Section

Veterinary Medicine

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