SERUM AND PERITONEAL FLUID BIOCHEMICAL MARKERS OF HORSES SUBMITTED TO INTESTINAL OBSTRUCTION

Authors

  • Paula Alessandra Di Filippo UENF
  • Aracele Elisane Alves FCAV, UNESP, jaboticabal, SP.
  • Larissa Correia Hermeto FCAV, UNESP, jaboticabal, SP.
  • Aureo Evangelista Santana FCAV, UNESP, jaboticabal, SP.

DOI:

https://doi.org/10.5216/cab.v13i4.14105

Keywords:

Animal Sanity

Abstract

Twenty-four horses were distributed into four different groups, instrumented control (GI), duodenum obstruction (GII), ileum obstruction (GIII) and large colon obstruction (GIV). Serum and peritoneal fluid analysis of aspartate aminotransferase, creatine kinase, lactate dehydrogenase, alkaline phosphatase, inorganic phosphorus and lactate were measured. Samples were collected one hour before the surgical procedure (T0); 3 hours after the obstruction (T3ob), 1, 3, 12, 24, 120 and 168 hours after the beginning of reperfusion/deobstruction. Duodenal (GII) and ileum (GIII) obstructions changed serum and peritoneal fluid  biochemical analysis. However, only lactate, lactate dehydrogenase, creatine kinase and inorganic phosphorus concentrations were abnormal in peritoneal fluid three hours after the obstruction. The biochemical analysis of peritoneal fluid allowed a faster diagnostic of intestinal alterations than the serum analysis; hence it should be prioritized when pre-operatory colic assessment is carried out.
KEYWORDS: biomarkers; colic; equine.

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Author Biographies

Paula Alessandra Di Filippo, UENF

Profa Dra de Clínica Cirúrgica Veterinária da Universidade Estadual do Norte Fluminense "Darcy Ribeiro", UENF, Campos dos Goytacazes, RJ.

Aracele Elisane Alves, FCAV, UNESP, jaboticabal, SP.

Pós-doutoranda em cirurgia veterinária pela FCAV, Unesp.

Larissa Correia Hermeto, FCAV, UNESP, jaboticabal, SP.

Doutoranda em cirurgia veterinária pela FCAV, Unesp.

Aureo Evangelista Santana, FCAV, UNESP, jaboticabal, SP.

Prof Dr. do Departamento de Clínica e Cirurgia Veterinária da Universidade Estadual Paulista, FCAV, UNESP, Jaboticabal, SP.

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Published

2012-12-14

How to Cite

DI FILIPPO, P. A.; ALVES, A. E.; HERMETO, L. C.; SANTANA, A. E. SERUM AND PERITONEAL FLUID BIOCHEMICAL MARKERS OF HORSES SUBMITTED TO INTESTINAL OBSTRUCTION. Brazilian Animal Science/ Ciência Animal Brasileira, Goiânia, v. 13, n. 4, p. 504–511, 2012. DOI: 10.5216/cab.v13i4.14105. Disponível em: https://revistas.ufg.br/vet/article/view/14105. Acesso em: 22 nov. 2024.

Issue

Vol. 13 No. 4 (2012)

Section

Veterinary Medicine

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