HISTOPHATOLOGICAL STUDY IN CORNEAS OF DOGS, TREATED WITH 2-1 DISSODIC FOSPHATE OF BETAMETHASONE AND DISSODIC FOSPHATED/ACETATE OF DEXAMETHASONE, THAT HAD RECEIVED IMPLANTATION OF SWINE CORNEAS

Authors

  • Nilo Sérgio Troncoso Chaves UFG
  • Paulo Sérgio de Moraes Barros FMVZ/USP
  • Apóstolo Ferreira Martins UFG
  • Eugênio Gonçalves de Araújo UFG
  • Larissa Franco de Araújo UFG
  • Duvaldo Eurides Universidade Federal de Uberlândia
  • Luiz Antônio Franco da Silva UFG

Keywords:

Histopatology, corticosteroids, xenotransplant, cornea, canine, swine

Abstract

Ten dogs, with no definitive breed, average weight of 10 kg, were in this research. After being examined and considered healthy they received numbers, from 11 to 20 in their collars. Each dog received implantation, in the left eye, of swine cornea, obtained at Casa de Banha Caçula, a slaughterhouse, and maintained in wet chamber for six hours at most. Before surgery, each animal received 4 mg of dissodic phosphate/acetate dexamethasone IM and, once a week one drop of dissodic phosphate betamethasone and gentamicin sulphate, four times a day, until the 28th day. when the animals were sacrificed through painless process (Thiopental sodic + succinilcolin chloride ), and the eye that had received the implantation of swine cornea was enucleated. Formaldehyde 10% was injected in the vitreous camera and after that the eye was placed in a container and the cornea was removed with sclerous ring, treated and colored with hematoxilin-eosin. The implantation and the cornea nearby areas were analysed as well as the alterations.

KEY-WORDS: Histopatology; corticosteroids; xenotransplant; cornea; canine; swine.

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Published

2007-12-17

How to Cite

CHAVES, N. S. T.; BARROS, P. S. de M.; MARTINS, A. F.; ARAÚJO, E. G. de; ARAÚJO, L. F. de; EURIDES, D.; SILVA, L. A. F. da. HISTOPHATOLOGICAL STUDY IN CORNEAS OF DOGS, TREATED WITH 2-1 DISSODIC FOSPHATE OF BETAMETHASONE AND DISSODIC FOSPHATED/ACETATE OF DEXAMETHASONE, THAT HAD RECEIVED IMPLANTATION OF SWINE CORNEAS. Pesquisa Agropecuária Tropical [Agricultural Research in the Tropics], Goiânia, v. 26, n. 2, p. 37–43, 2007. Disponível em: https://revistas.ufg.br/pat/article/view/2935. Acesso em: 17 jul. 2024.

Issue

v. 26, n. 2, Jul./Dec. 1996

Section

Research Article

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