GOSSIPOL EFFECT ON MICE (Mus domesticus domesticus) BLOOD

Authors

  • Reginaldo Nassar Ferreira UFG
  • Liliane Araújo Mendes de Almeida UFG
  • Rejane Costa Ferreira CNPq

Keywords:

Gossipol, mice, blood

Abstract

Twenty thirty day-old male mice weighing 25 g were divided in two groups: Group 1: oral saline solution (control), and Group 2: oral gossipol acetic-acid at 20 mg/kg. Forty days after treatments and leukocytes were counted through Newbawer counting chamber. Leukometry showed 9,241 leukocytes/mm3 for the control and 6,125 leukocytes/mm3 for the gossipol treated group (significant difference for P=0.05). Erythrometry showed 6,596,000 erythrocytes/mm3 and 6,399,000 erythrocytes/mm3 for control and gossipol treated mice, respectively. It was concluded that gossipol may induce a deleterious effect on the organism defense cells.

KEY-WORDS: Gossipol; mice; blood.

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Published

2007-12-12

How to Cite

FERREIRA, R. N.; ALMEIDA, L. A. M. de; FERREIRA, R. C. GOSSIPOL EFFECT ON MICE (Mus domesticus domesticus) BLOOD. Pesquisa Agropecuária Tropical [Agricultural Research in the Tropics], Goiânia, v. 25, n. 1, p. 63–68, 2007. Disponível em: https://revistas.ufg.br/pat/article/view/2736. Acesso em: 25 nov. 2024.

Issue

v. 25, n. 1, Jan./Jun. 1995

Section

Research Article

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