CIRCULATING PROFILE OF ROTAVIRUS A, G AND P GENOTYPES BEFORE AND AFTER VACCINE INTRODUCTION IN THE BRAZILIAN MID-WEST 1986-2015
DOI:
https://doi.org/10.5216/rpt.v46i1.46300Palavras-chave:
Rotavirus infections, genotype, vaccination.Resumo
The purpose of this study was to perform a comparative analysis of Rotavirus A (RVA) G and P genotypes circulating in the Brazilian Mid-West in the period 1986-2015. Seven studies conducted from 1986 to 2009 were included, as well as fecal samples obtained in the period 2014-2015. RVA was screened by ELISA and/or PAGE; genotyping by conventional RT-PCR and/or genomic sequencing. A temporal variation in the predominance of G genotypes mainly G1 and G2 with G9 and G12 emergence was observed. Even with vaccination, RVA continues
to circulate in the population, requiring continuous virus monitoring.
Downloads
Downloads
Publicado
Como Citar
Edição
Seção
Licença
The manuscript submission must be accompanied by a letter signed by all authors stating their full name and email address, confirming that the manuscript or part of it has not been published or is under consideration for publication elsewhere, and agreeing to transfer copyright in all media and formats for Journal of Tropical Pathology.