Clinical conditions and metabolic profile of preterm newborns from birth to six months of corrected age

Abstract

The survival of preterm newborns and low weight has shownthe metabolic changes throughout their lives. The objective is to correlate if the clinical conditions of the preterm newborn (PTNB) at birth, during admission and after discharge from the Neonatal Intensive Care Unit, influence their metabolic profile at six months of Corrected Age. It is aprospective cohort studywith 37 PTNB. The statistical analysis was descriptive and inferential. When correlating the clinical conditions at birth, during admission and at follow-up with the PTNB metabolic profile, the necrotizing enterocolitis(p=0.006) and late sepsis (p= 0.02) presented a significantstatistical difference in the insulin concentration. The glycemic profile in the presence of comorbidities stayed normaland the lipidic profile gradually increased. The PTNB of this study constitutesa group at risk for the development of metabolic syndrome and cardiovascular diseases, due to lipidic and insulinchanges found.