Antimicrobial resistance of Staphylococcus aureus isolates obtained from healthy newborns

Abstract

Oxacillin resistant Staphylococcus aureus is a major pathogen associated with the etiology of nosocomial infections. Transmission of S.aureus may occur in newborns during delivery, however, it can also occur through contact with relatives, healthcare professionals and the environment. This study was carried out in a University hospital from February to April of 2007, in order to investigate the frequency of S.aureus nasal carriers among healthy newborns; the profile of susceptibility of isolated species to the antibiotics usually administered in clinical practice; and to identify the presence of gene which encodes resistance to Oxacillin (mecA gene). Staphylococcus aureus was isolated in 45 (90%), out of the 50 subjects investigated. Oxacillin resistance, determined by measuring the Minimum Inhibitory Concentration, was observed in 5 samples (11.1%). In 4 of the samples analyzed (80%), it was detected the presence of the mecA gene. Therefore, healthcare professionals are advised to take particular attention in order to identify the bearers/carriers of S. aureus, since such professionals are directly involved in providing care to patients; thus they must take precautions to control and prevent the germ spread.