Evaluation of prophylactic antibiotics for surgery in an university hospital

Authors

  • Adriana Oliveira Guilarde
  • Isabela Theodoro Pacheco
  • Lívia Vanessa Ribeiro Gomes
  • Vinícius Araújo Barbosa de Lima
  • Josela Palmeira Pacheco
  • Marta Antunes de Souza

DOI:

https://doi.org/10.5216/rpt.v38i3.8124

Keywords:

Antibiotic, Prophylaxis, Surgery

Abstract

The inappropriate prescription of prophylactic antibiotics favors selection of resistant
bacteria. We aimed to characterize the inappropriate prescription of prophylactic
antibiotics; their indication, selected spectrum, dose and duration of prophylaxis
in an university hospital in Goiania, Brazil. We also aimed to propose adjustments
in the requirements for prescription, according to the literature. Through structured
questionnaire the specialty in which the antibiotic was prescribed, type of surgery,
indications, spectrum of action, dose and specified duration were evaluated. 203
surgical procedures were evaluated (64% clean surgery, 30% clean-contaminated
and 6% contaminated). Cefazolin was the antibiotic most used (92%). Inappropriate
prescribing was found in 75% of cases, from those 77% were due to the excessive
duration of administration of the antimicrobial agent. In 18% of surgeries there was
no indication of prophylaxis and in 9% suboptimal doses of antimicrobial were used.
The estimated additional cost of requirements not indicated and excessive duration
was equivalent to US$ 800.00. We recognize the need for a joint working committee
between surgical and hospital infection control teams, enabling reduction of costs
and avoiding selection of resistant bacterial strains, among other adverse effects.

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Published

2009-11-12

How to Cite

GUILARDE, A. O.; PACHECO, I. T.; GOMES, L. V. R.; LIMA, V. A. B. de; PACHECO, J. P.; SOUZA, M. A. de. Evaluation of prophylactic antibiotics for surgery in an university hospital. Revista de Patologia Tropical / Journal of Tropical Pathology, Goiânia, v. 38, n. 3, p. 179–186, 2009. DOI: 10.5216/rpt.v38i3.8124. Disponível em: https://revistas.ufg.br/iptsp/article/view/8124. Acesso em: 19 oct. 2024.

Issue

Vol. 38 No. 3 (2009)

Section

ORIGINAL ARTICLES

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