Visceral leishmaniasis in Brazil: scenarios and challenges for the surveillance and control

Authors

  • Mauro Celio de Almeida Marzochi Fundação Oswaldo Cruz (FIOCRUZ), Instituto Nacional de Infectologia Evandro Chagas, Laboratório de Pesquisa Clínica e Vigilância em leishmanioses, Rio de Janeiro, Rio de Janeiro, Brasil https://orcid.org/0000-0002-5969-0654
  • David Soeiro Barbosa Universidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Parasitologia, Belo Horizonte, Minas Gerais, Brasil https://orcid.org/0000-0002-5241-5940
  • Vinicius Silva Belo Universidade Federal de São João del Rei, Departamento de Ciências da Saúde, Divinópolis, Minas Gerais, Brasil https://orcid.org/0000-0003-0183-1175
  • Giovanna Rotondo de Araújo Universidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Parasitologia, Belo Horizonte, Minas Gerais, Brasil https://orcid.org/0000-0002-7513-5087
  • Aline Fagundes da Silva Fundação Oswaldo Cruz (FIOCRUZ), Instituto Nacional de Infectologia Evandro Chagas, Laboratório de Pesquisa Clínica e Vigilância em leishmanioses, Rio de Janeiro, Rio de Janeiro, Brasil https://orcid.org/0000-0001-7345-0350
  • Maria Inês Pimentel Fundação Oswaldo Cruz (FIOCRUZ), Instituto Nacional de Infectologia Evandro Chagas, Laboratório de Pesquisa Clínica e Vigilância em leishmanioses, Rio de Janeiro, Rio de Janeiro, Brasil https://orcid.org/0000-0002-8159-0502
  • Keyla Belizia Feldman Marzochi Fundação Oswaldo Cruz (FIOCRUZ), Instituto Nacional de Infectologia Evandro Chagas, Laboratório de Pesquisa Clínica e Vigilância em leishmanioses, Rio de Janeiro, Rio de Janeiro, Brasil https://orcid.org/0000-0001-9080-216X

Abstract

Adaptation of the vector and displacement of infected dogs to previously disease-free areas challenges visceral leishmaniasis (VL) control, and leads to geographic dispersion and occurrence in urban and peri-urban areas. Continuous VL control measures over time must be applied with a wide geographic reach, along with better diagnosis practices and timely treatment. The high case-fatality of human VL in areas of recent introduction and its growing association with HIV impose the need for an early diagnosis, treatment and the adoption of active search for human and canine cases incorporated into the routine of periodic home visits by health professionals. The increasing on public rejection of canine euthanasia as a control measure, the limitations of canine therapy with the current available drugs, and the controversies regarding available vaccines for canine protection are discussed. Good prospects on the insecticide-impregnated collars as an effective control measure are emphasized.

KEY WORDS: Leishmaniasis; visceral; epidemiology; public health surveillance; Kalazar.

Downloads

Download data is not yet available.

Downloads

Published

2023-03-09

How to Cite

DE ALMEIDA MARZOCHI, M. C.; SOEIRO BARBOSA, D.; SILVA BELO, V.; ROTONDO DE ARAÚJO, G.; FAGUNDES DA SILVA, A.; PIMENTEL, M. I.; BELIZIA FELDMAN MARZOCHI, K. Visceral leishmaniasis in Brazil: scenarios and challenges for the surveillance and control . Revista de Patologia Tropical / Journal of Tropical Pathology, Goiânia, v. 52, n. 1, p. 1–10, 2023. Disponível em: https://revistas.ufg.br/iptsp/article/view/74769. Acesso em: 22 dec. 2024.

Issue

Vol. 52 No. 1 (2023)

Section

REVIEW

License

The manuscript submission must be accompanied by a letter signed by all authors stating the full name and email address, confirming that the material has not been published or is under consideration for publication elsewhere, and agreeing to transfer copyright in all media and formats for Journal of Tropical Pathology. The authors will not be paid for published articles. They are solely responsible for the content of those articles, even if the Editor holds the right to adjust them to the norms of the journal.

The reviewers will not be paid for the peer review process.