Enteroaggregative Escherichia coli (EAEC): phylotyping and antibiotics resistance in an emergent enteropathogen

Authors

  • Adriana Hamond Regua-Mangia
  • Rose Mary Pimentel Bezerra
  • Carmen Macedo Esparis
  • Lúcia Martins Teixeira

DOI:

https://doi.org/10.5216/rpt.v38i1.6218

Keywords:

Enteroaggregative Escherichia coli, Antibiotics resistance, PCR, Phylotyping, Virulence.

Abstract

Enteroaggregative Escherichia coli (EAEC) is an emerging enteropathogen
mainly in developing countries. The virulence mechanisms of EAEC are not
completely understood and the role of various factors described still requires further
investigation. Enteropathogenicity appears to be an attribute of certain subgroups
within the category and resistance to antibiotics has been identified as a relevant
characteristic among EAEC strains. Phylogenetic studies have shown that E. coli
can be divided into four main groups designated A, B1, B2 and D. The purpose of
this study was to determine the phylogenetic group and resistance to antibiotics in
EAEC isolates obtained from children with diarrheal disease and control subjects by
polymerase chain reaction and standard disk diffusion method. Phylotyping revealed
a bacterial population distributed in phylogenetic groups A (65.8%), D (20.7%), B1
(9.7%) and B2 (3.6%). Antimicrobial resistance was observed in 65.9% of the
bacterial population. Multidrug resistance phenotype was detected mainly among
EAEC isolated from diarrheal children and belonging to phylogenetic groups A and D. The data contribute to the knowledge of genetic epidemiological aspects of these
enteropathogens circulating in our community.

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Published

2009-05-11

How to Cite

REGUA-MANGIA, A. H.; BEZERRA, R. M. P.; ESPARIS, C. M.; TEIXEIRA, L. M. Enteroaggregative Escherichia coli (EAEC): phylotyping and antibiotics resistance in an emergent enteropathogen. Revista de Patologia Tropical / Journal of Tropical Pathology, Goiânia, v. 38, n. 1, p. 27–34, 2009. DOI: 10.5216/rpt.v38i1.6218. Disponível em: https://revistas.ufg.br/iptsp/article/view/6218. Acesso em: 17 jul. 2024.

Issue

Vol. 38 No. 1 (2009)

Section

ORIGINAL ARTICLES

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