the female genital tract mucosa immune system and the impact of the sexually transmitted diseases

Authors

  • Yanna Andressa Ramos de Lima
  • Maria de Fátima Costa Alves

DOI:

https://doi.org/10.5216/rpt.v37i4.5661

Keywords:

Female genital tract, Mucosal immunity, Sexually transmitted infections.

Abstract

The female genital tract mucosa is the main access for sexually transmitted
pathogens and is also the site of development of the semi-allogenic embryo. To deal
with these functions, the immune system associated with the female genital mucosa
has certain characteristics that differentiate it from the immune system associated
with the gastrointestinal tract. The female sex hormones may interfere with the
immunological aspects of this system, and the distribution of cells distinguishes
it from other mucosal sites. Also, in the female genital mucosa the organized
lymphoid areas as the Peyer’s patches in the intestine are missing, and the main type
of immunoglobulin found in cervical and vaginal secretions is IgG in contrast to the
predominant IgA in saliva, tears and other biological secretions. The purpose of this
review is to present the key features already observed with respect to aspects of the
immune response in the female genital tract and highlight the impact of sexually
transmitted diseases (STD) on this mucosal immune site.

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Published

2009-03-05

How to Cite

LIMA, Y. A. R. de; ALVES, M. de F. C. the female genital tract mucosa immune system and the impact of the sexually transmitted diseases. Revista de Patologia Tropical / Journal of Tropical Pathology, Goiânia, v. 37, n. 4, p. 295–310, 2009. DOI: 10.5216/rpt.v37i4.5661. Disponível em: https://revistas.ufg.br/iptsp/article/view/5661. Acesso em: 19 may. 2024.

Issue

Vol. 37 No. 4 (2008)

Section

UP TO DATE

License

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