NON-Aspergillus FUNGAL RHINOSINUSITIS AT A TERTIARY CARE HOSPITAL AND THE FIRST REPORT OF HUMAN INFECTION BY Trichoderma asperellum

Authors

  • Isabel Cristina Espíndola Cardoso Programa de Pós-Graduação em Ciências Pneumológicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul (UFRGS), Brazil
  • Cecília Bittencourt Severo Laboratório de Micologia, Hospital Santa Rita, Irmandade Santa Casa de Misericórdia Porto Alegre (ISCMPA), RS, Brazil and Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Brazil.
  • Flávio de Mattos Oliveira Laboratório de Micologia, Hospital Santa Rita, Irmandade Santa Casa de Misericórdia Porto Alegre (ISCMPA), RS, Brazil.
  • Elizabeth Araújo Núcleo de Otorrinolaringologia do Hospital Moinhos de Vento, Porto Alegre, Brazil.
  • Bruno Hochhegger Serviço de Radiologia, ISCMPA, RS, Brazil
  • Klaus Loureiro Irion Department of Tropical Medicine, Liverpool Heart and Chest Hospital, Liverpool University, United Kingdom
  • Luiz Carlos Severo Departamento de Ciências Pneumológicas, UFRGS, Porto Alegre, Brazil

DOI:

https://doi.org/10.5216/rpt.v44i4.39232

Keywords:

Sinus, sinusitis, non-Aspergillus rhinosinusitis, Trichoderma asperellum.

Abstract

We describe 27 cases of fungal rhinosinusitis, which were caused by agents other than Aspergillus, diagnosed at our institution during a 24-year period. Particular focus was on defining the causal fungi and the predisposing factors. Fungal cultures were obtained from 20 cases and there was no growth in seven cases. Classification of mycotic disease of the nose and paranasal sinuses as invasive and noninvasive is based on clinical, radiological, and histopathological factors. The most common pathogens were Histoplasma capsulatum (n=4), Scedosporium apiospermum (n=2), Alternaria alternata (n=2), Schizophyllum commune (n=2), Pseudallescheria boydii (n=1), Penicillium sp. (n=1), Lichtheimia (Absidia) corymbifera (n=1), Xylaria enteroleuca (n=1), Trichoderma asperellum (n=1), T. harzianum (n=1), T. viride (n=1), Fusarium solani (n=1), Cladosporium sp. (n=1), and Cryptococcus neoformans (n=1). From the ones that revealed no growth, four were classified as hyalohyphomycosis and three were mucormycosis by the histopathological findings. In addition, we describe the first welldocumented case of rhinosinusitis and human infection by T. asperellum.

Downloads

Download data is not yet available.

Downloads

Published

2015-12-28

How to Cite

CARDOSO, I. C. E.; SEVERO, C. B.; OLIVEIRA, F. de M.; ARAÚJO, E.; HOCHHEGGER, B.; IRION, K. L.; SEVERO, L. C. NON-Aspergillus FUNGAL RHINOSINUSITIS AT A TERTIARY CARE HOSPITAL AND THE FIRST REPORT OF HUMAN INFECTION BY Trichoderma asperellum. Revista de Patologia Tropical / Journal of Tropical Pathology, Goiânia, v. 44, n. 4, p. 395–408, 2015. DOI: 10.5216/rpt.v44i4.39232. Disponível em: https://revistas.ufg.br/iptsp/article/view/39232. Acesso em: 18 may. 2024.

Issue

Vol. 44 No. 4 (2015)

Section

ORIGINAL ARTICLES

License

The manuscript submission must be accompanied by a letter signed by all authors stating the full name and email address, confirming that the material has not been published or is under consideration for publication elsewhere, and agreeing to transfer copyright in all media and formats for Journal of Tropical Pathology. The authors will not be paid for published articles. They are solely responsible for the content of those articles, even if the Editor holds the right to adjust them to the norms of the journal.

The reviewers will not be paid for the peer review process.