TOXOPLASMA GONDII: IGG AND IGM IN CANCER PATIENTS IN SOUTHERN RIO GRANDE DO SUL

Authors

  • Jaqueline Radin Departamento de Microbiologia e Parasitologia, Instituto de Biologia, Universidade Federal de Pelotas, Brasil
  • Vanessa Radin Faculdade de Farmácia, Universidade Católica de Pelotas, Brasil
  • Beatris González Cademartori Departamento de Microbiologia e Parasitologia, Instituto de Biologia, Universidade Federal de Pelotas, Brasil
  • Juliana Carriconde Hernandes Departamento de Microbiologia e Parasitologia, Instituto de Biologia, Universidade Federal de Pelotas, Brasil
  • Michele Marques Noedel Laboratório Escola de Análises Clínicas do Hospital Universitário São Francisco de Paula, Universidade Católica de Pelotas, Brasil
  • Rodrigo Pereira de Oliveira Laboratório Escola de Análises Clínicas do Hospital Universitário São Francisco de Paula, Universidade Católica de Pelotas, Brasil
  • Claudiomar Soares Brod Departamento de Microbiologia e Parasitologia, Instituto de Biologia, Universidade Federal de Pelotas, Brasil

DOI:

https://doi.org/10.5216/rpt.v44i3.38019

Keywords:

Toxoplasma gondii, seroprevalence, neoplasia, immunosuppression

Abstract

Toxoplasmosis is an infection caused by the protozoan Toxoplasma gondii, which causes opportunistic infections in immunocompromised patients. The objective of this study was to verify IgG and IgM antibody positivity for T. gondii in patients with malignancies who underwent chemotherapy treatment at the Federal University Hospital of Pelotas, and the Center for Radiotherapy and Oncology at the Santa Casa de Misericordia in Pelotas. Serological tests for detection of antibodies in 77 samples were performed using the electro-chemiluminescence technique. It was found that the rate of seropositive antibodies for IgG was 90.9% and 7.8% for IgM. In accordance with the risk factors, on analysing the seropositives for anti-T. gondii IgG the significant difference (p<0.05) was only found in the age variable. The results indicate the need for serologic management of patients undergoing chemotherapy to prevent serious and even fatal consequences.

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How to Cite

RADIN, J.; RADIN, V.; CADEMARTORI, B. G.; HERNANDES, J. C.; NOEDEL, M. M.; DE OLIVEIRA, R. P.; BROD, C. S. TOXOPLASMA GONDII: IGG AND IGM IN CANCER PATIENTS IN SOUTHERN RIO GRANDE DO SUL. Revista de Patologia Tropical / Journal of Tropical Pathology, Goiânia, v. 44, n. 3, p. 271–281, 2015. DOI: 10.5216/rpt.v44i3.38019. Disponível em: https://revistas.ufg.br/iptsp/article/view/38019. Acesso em: 22 dec. 2024.

Issue

Vol. 44 No. 3 (2015)

Section

ORIGINAL ARTICLES

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