Analysis of parasitological techniques in the monitoring of patients with Chagas disease and treated by heart transplantation

Authors

  • Lucia Maria Almeida Braz
  • Soraya Kodja Makhoul Dias
  • Erika Gakiya
  • Rita Cristina Bezerra
  • Fátima das Dores Cruz
  • Silvia Moreira Ayub-Ferreira
  • Edimar Alcides Bocchi
  • Vicente Amato Neto

DOI:

https://doi.org/10.5216/rpt.v42i1.23594

Keywords:

Chagas disease, Heart transplantation, Reactivation, Xenodiagnosis, Hemoculture, Buffy coat.

Abstract

This study aimed to evaluate and make a comparison between hemoculture, xenodiagnosis and buffy coat examinations for diagnosis and monitoring of possible re-activation in chronic patients treated by heart transplantation. Seventy samples were analyzed and 15.7% (11/70) were positive:8.5% (6/70) in the hemocultures and 12.8% (9/70) in the xenodiagnosis. Four samples were positive in both techniques (5.7%). There were no positive results for the buffy coat examination. These findings support information about the superior sensitivity of xenodiagnosis in relation to hemoculture. Positive xenodiagnosis (day 15) and a myocarditis with nests of amastigotes, 15 days before the laboratory detection, observed in patient sample 20, signals the importance of early reading of indirect parasitological examinations as possible predictors of disease reactivation.

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How to Cite

BRAZ, L. M. A.; DIAS, S. K. M.; GAKIYA, E.; BEZERRA, R. C.; CRUZ, F. das D.; AYUB-FERREIRA, S. M.; BOCCHI, E. A.; AMATO NETO, V. Analysis of parasitological techniques in the monitoring of patients with Chagas disease and treated by heart transplantation. Revista de Patologia Tropical / Journal of Tropical Pathology, Goiânia, v. 42, n. 1, 2013. DOI: 10.5216/rpt.v42i1.23594. Disponível em: https://revistas.ufg.br/iptsp/article/view/23594. Acesso em: 21 nov. 2024.

Issue

Vol. 42 No. 1 (2013)

Section

ORIGINAL ARTICLES

License

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