Investigation in autopsy material on the hypothesis of the association between obesity and neurocysticercosis
DOI:
https://doi.org/10.5216/rpt.v40i1.13920Keywords:
Neurocysticercosis, Obesity, Hypothalamus.Abstract
Introduction: Neurocysticercosis (NCC) is an infection of the Central NervousSystem that may be associated with obesity when the cysticercus affects
hypothalamic centers associated to the appetite and satiety. Aim: to compare the
Body Mass Index (BMI) of autopsied patients with NCC (except hypothalamic)
with an autopsied group without cysticercosis. Methods: 2,629 protocols from
autopsies from 1970 until 2004 were revised and the following variables evaluated:
BMI, positive diagnosis, and localization of neurocysticercosis. NCC was found in
71 autopsies (2.7%). The median BMI of the group with NCC, which was 19.06
kg/m2, was significantly lower (p=0.001) in comparison with the group without
cysticercosis with a BMI of 20.76 kg/m2. Conclusion: NCC itself is not related to
obesity, except when the cysticercus has hypothalamic localization.
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