Disseminated sporotrichosis, with cutaneous and visceral involvement
DOI:
https://doi.org/10.5216/rpt.v40i1.13917Keywords:
Disseminated sporotrichosis, Sporothrix schenckii, Skin gummata.Abstract
A case of cutaneous disseminated sporotrichosis with visceral involvement ispresented. The patient was a 38 year old man, without previous immunological
alterations. He presented several skin nodules and gummata which evolved to skin
ulcers. He also exhibited fever, weight loss, anemia, edema, hepatosplenomegaly, and
multiple adenomegalies, excavated infiltrates in the right lung, hypoalbuminemia,
albuminuria and hematuria. Sporothrix schenckii was isolated from gummata
secretion of several skin lesions and specific antibodies were detected by
immunodiffusion in agar gel and counterimmunoelectrophoresis with secondary
immunodiffusion in agarose, using a S. schenckii metabolic antigen. The isolate was
identified as Sporothrix schenckii sensu stricto, which is the most frequently isolated
in Argentina. The patient was treated with amphotericin B-deoxycholate and amphotericin B colloidal dispersion intravenously, later he received itraconazole by
oral route with good clinical response.
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