O pH da região vulvar no ciclo vital: revisão de escopo

Autores

  • Maristela Belletti Mutt Urasaki Universidade de São Paulo (USP), Escola de Artes, Ciências e Humanidades, São Paulo, São Paulo, Brasil. E-mail: mari.urasaki@usp.br. https://orcid.org/0000-0002-5034-3402
  • Euzeli da Silva Brandão Universidade Federal Fluminense (UFF), Niterói, Rio de Janeiro, Brasil. E-mail: euzelibrandao@id.uff.br. https://orcid.org/0000-0001-8988-8103
  • Rosemeire Sartori de Albuquerque Universidade de São Paulo (USP), Escola de Artes, Ciências e Humanidades, São Paulo, São Paulo, Brasil. E-mail: rosemeiresartori@usp.br. https://orcid.org/0000-0001-8593-5080
  • Lorrany Magalhães Masson Universidade de São Paulo (USP), Escola de Artes, Ciências e Humanidades, São Paulo, São Paulo, Brasil. E-mail: lorranym.masson@gmail.com. https://orcid.org/0009-0007-4612-7110
  • Jessica da Silva Almeida Universidade de São Paulo (USP), Escola de Artes, Ciências e Humanidades, São Paulo, São Paulo, Brasil. E-mail: jessyalmeida@usp.br. https://orcid.org/0009-0000-0925-6369

DOI:

https://doi.org/10.5216/ree.v26.75717

Palavras-chave:

Vulva, Concentração de Íons de Hidrogênio, Pele, Higiene, Pesos e Medidas

Resumo

Introdução: mapear os estudos que mensuraram o potencial Hidrogeniônico (pH) da região vulvar no ciclo vital da mulher. Métodos: revisão de escopo conforme recomendações do Manual for Evidence Synthesis do Joanna Briggs Institute (JBI), nas bases SCOPUS, Web of Science, Academic Search Premier, PubMed, Bielefeld Academic Search Engine e Google Acadêmico em janeiro de 2022. Foram incluídos estudos publicados em português, espanhol, francês e inglês, sem limite temporal. Resultados: dos 954 documentos recuperados, 13 foram selecionados. Apurou- se que os estudos utilizaram diferentes procedimentos para as medições quanto aos equipamentos, ambiente e preparo das participantes. A média de idade apresentada pela população feminina estudada variou entre 31 e 43 anos. Os locais de medição vulvar foram os grandes e pequenos lábios, dobra interlabial e períneo. O menor valor do pH aferido foi 4,6 e o maior 6,3. Conclusões:constatou-se baixa produção de estudos acerca do pH vulvar e ênfase das pesquisas na população de mulheres adultas. A diversidade de procedimentos e locais de aferição encontrados não permite afirmações seguras sobre uma faixa de valor de pH da superfície da pele vulvar.

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Referências

Farage MA, Maibach HI. Tissue structure and physiology of the vulva. In: Farage MA, Maibach HI, editors. The vulva: physiology and clinical management. Boca Raton: CRC Press; 2017. p. 6-13. https://doi.org/10.1201/9781315113739

Farage MA, Lennon L, Ajayi F. Products used on female genital mucosa. Curr Probl Dermatol. 2011;40:90-100. https://doi.org/10.1159/000321058

Al-Niaimi F, Felton S, Williams J. Patch testing for vulval symptoms: our experience with 282 patients. Clin Exp Dermatol. 2014 June;39(4):439-42. https://doi.org/10.1111/ced.12330

Federação Brasileira das Associações de Ginecologia e Obstetrícia (FEBRASGO). Guia prático de condutas. Higiene genital feminina [Internet]. 2009 [cited 2022 Sep 15]. Available from: https://missali.site.med.br/fmfiles/index.asp/::XPR3638::/Guia_de_Higiene_Feminina.pdf

Earage MA. Vulvar susceptibility to contact irritants and allergens: a review. Arch Gynecol Obstet. 2005;272(2):167- 72. https://doi.org/10.1007/s00404-005-0732-4

Proksch E. pH in nature, humans and skin. J Dermatol. 2018 Sep;45(9):1044-52. https://doi.org/10.1111/1346-8138.14489

du Plessis JL, Stefaniak AB, Wilhelm KP. Measurement of skin surface pH. Curr Probl Dermatol. 2018;54:19-25. https://doi.org/10.1159/000489514

Ali SM, Yosipovitch G. Skin pH: from basic science to basic skin care. Acta Derm Venereol. 2013 May;93(3):261-7. https://doi.org/10.2340/00015555-1531

van Rensburg SJ, Franken A, Du Plessis JL. Measurement of transepidermal water loss, stratum corneum hydration and skin surface pH in occupational settings: a review. Skin Res Technol. 2019 Sep;25(5):595-605. https://doi.org/10.1111/srt.12711

Chen Y, Bruning E, Rubino J, Eder SE. Role of female intimate hygiene in vulvovaginal health: global hygiene practices and product usage. Womens Health (Lond). 2017 Dec;13(3):58- 67. https://doi.org/10.1177/1745505717731011

Umami A, Paulik E, Molnár R, Murti B. The relationship between genital hygiene behaviors and genital infections among women: a systematic review. Journal Ners. 2022;17(1):89- 101. https://doi.org/10.20473/jn.v17i1.34402

Felix TC, Araújo LB, Röder DVDB, Pedroso RS. Evaluation of vulvovaginitis and hygiene habits of women attended in primary health care units of the family. Int J Womens Health. 2020 Jan;12:49-57. https://doi.org/10.2147/IJWH.S229366

Summers PR, Hunn J. Unique dermatologic aspects of the postmenopausal vulva. Clin Obstet Gynecol. 2007 Sep;50(3):745-51. https://doi.org/10.1097/GRF.0b013e3180db96ae

van der Meijden WI, Boffa MJ, Ter Harmsel B, Kirtschig G, Lewis F, Moyal-Barraco M, et al. 2021 European guideline for the management of vulval conditions. J Eur Acad Dermatol Venereol. 2022;36(6):952-72. https://doi.org/10.1111/jdv.18102

Royal College of Obstetricians & Gynaecologists. The management of vulval skin disorders [Internet]. RCOG; 2011 [cited 2022 Dez 13] Available from: https://bssvd.org/wp-content/uploads/2018/06/RCOG-Vulval- Guidelines-1.pdf

Kaur J, Kalsy J. Study of pruritus vulvae in geriatric age group in tertiary hospital. Indian J Sex Transm Dis AIDS. 2017 Jan-Jun;38(1):15-21. https://doi.org/10.4103/0253-7184.192632

Edwards D, Panay N. Treating vulvovaginal atrophy/ genitourinary syndrome of menopause: how important is vaginal lubricant and moisturizer composition? Climacteric. 2015 Apr;19(2):151-61. https://doi.org/10.3109/13697137.2015.1124259

Peters MDJ, Godfrey C, McInerney P, Munn Z, Tricco AC, Khalil H. Chapter 11: Scoping Reviews (2020 version) [Internet]. In: Aromataris E, Munn Z, editors. JBI Manual for Evidence Synthesis. JBI; 2020 [cited 2022 Dec 13]. Available from: https://synthesismanual.jbi.global/

Murina F, Caimi C, Felice R, Di Francesco S, Cetin I. Characterization of female intimate hygiene practices and vulvar health: a randomized double-blind controlled trial. J Cosmet Dermatol. 2020 Oct;19(10):2721-6. https://doi.org/10.1111/jocd.13402

Bruning E, Chen Y, McCue KA, Rubino JR, Wilkinson JE, Brown ADG. A 28 day clinical assessment of a lactic acid-containing antimicrobial intimate gel wash formulation on skin tolerance and impact on the vulvar microbiome. Antibiotics (Basel). 2020 Feb;9(2):55. https://doi.org/10.3390/antibiotics9020055

Vongsa R, Hoffman D, Shepard K, Koenig D. Comparative study of vulva and abdominal skin microbiota of healthy females with high and average BMI. BMC Microbiol. 2019 Jan;19(1):16. https://doi.org/10.1186/s12866-019-1391-0

Miyamoto T, Akiba S, Sato N, Fujimura T, Takagi Y, Kitahara T, et al. Study of the vulvar skin in healthy Japanese women: components of the stratum corneum and microbes. Int J Dermatol. 2012 Dec;52(12):1500-5. https://doi.org/10.1111/j.1365-4632.2012.05582.x

Fujimura T, Sato N, Ophaswongse S, Takagi Y, Hotta M, Kitahara T, et al. Characterization of vulvar skin of healthy Thai women: influence of sites, age and menopause. Acta Derm Venereol. 2013 Mar;93(2):242-5. https://doi.org/10.2340/00015555-1534

Fujimura T, Sato N, Takagi Y, Ohuchi A, Kawasaki H, Kitahara T, et al. An investigator blinded cross-over study to characterize the cutaneous effects and suitability of modern sanitary pads for menstrual protection for women residing in the USA. Cutan Ocul Toxicol. 2011 Sep;30(3):205-11. https://doi.org/10.3109/15569527.2011.554936

Löwhagen GB, Bonde E, Forsgren-Brusk U, Runeman B, Tunbäck P. The microenvironment of vulvar skin in women with symptomatic and asymptomatic herpes simplex virus type 2 (HSV-2) infection. J Eur Acad Dermatol Venereol. 2006 Oct;20(9):1086-9. https://doi.org/10.1111/j.1468-3083.2006.01729.x

Runeman B, Rybo G, Forsgren-Brusk U, Larkö O, Larsson P, Faergemann J. The vulvar skin microenvironment: impact of tight-fitting underwear on microclimate, pH and microflora. Acta Derm Venereol. 2005;85(2):118-22. https://doi.org/10.1080/00015550410024562

Runeman B, Rybo G, Forsgren-Brusk U, Larkö O, Larsson P, Faergemann J. The vulvar skin microenvironment: influence of different panty liners on temperature, pH and microflora. Acta Derm Venereol. 2004;84(4):277-84. https://doi.org/10.1080/200484277284

Runeman B, Rybo G, Larkö O, Faergemann J. The vulva skin microclimate: influence of panty liners on temperature, humidity and pH. Acta Derm Venereol. 2003;83(2):88-92. https://doi.org/10.1080/00015550310007409

Wilhelm D, Elsner P, Maibach HI. Standardized trauma (tape stripping) in human vulvar and forearm skin. Effects on transepidermal water loss, capacitance and pH. Acta Derm Venereol. 1991;71:123-6. PMID: 1675519.

Elsner P, Wilhelm D, Maibach HI. Multiple parameter assessment of vulvar irritant contact dermatitis. Contact Dermatitis. 1990 July;23(1):20-6. https://doi.org/10.1111/j.1600-0536.1990.tb00078.x

Elsner P, Maibach HI. The effect of prolonged drying on transepidermal water loss, capacitance and pH of human vulvar and forearm skin. Acta Derm Venereol. 1990;70(2):105-9. PMID: 1969192.

Kaur P, Patil RK, Bansal R, Patil HC. A review of practices related to genital hygiene and its awareness in women. Panacea Journal of Medical Sciences. 2021;11(3):366-9. https://doi.org/10.18231/j.pjms.2021.074

Voegeli R, Gierschendorf J, Summers B, Rawlings AV. Facial skin mapping: from single point bio-instrumental evaluation to continuous visualization of skin hydration, barrier function, skin surface pH, and sebum in different ethnic skin types. Int J Cosmet Sci. 2019 Oct;41(5):411-24. https://doi.org/10.1111/ics.12562

Monti M. Chamomile extract in a cleansing wash (Saugella Poligyn) in menopause hygiene. Global Science Research Journals [Internet]. 2016;4(1):162-6.

Banga L. The microbiota of the vulva and vagina: ways of washing to optimise the protective function of the vulvo- vaginal microbiota during pregnancy. New Zealand College of Midwives Journal. 2021;57:34-40. https://doi.org/10.12784/nzcomjnl57.2021.5.34-40

Attieh E, Maalouf S, Roumieh D, Abdayem P, Abitayeh G, Kesrouani A. Feminine hygiene practices among female patients and nurses in Lebanon. Reprod Health. 2016 May;13(1):59. https://doi.org/10.1186/s12978-016-0182-4

Stefaniak AB, du Plessis J, John SM, Eloff F, Agner T, Chou TC, et al. International guidelines for the in vivo assessment of skin properties in non-clinical settings: part 1. pH. Skin Res Technol. 2012 Dec 26;19(2):59-68. https://doi.org/10.1111/srt.12016

Parra JL, Paye M; EEMCO Group. EEMCO guidance for the in vivo assessment of skin surface pH. Skin Pharmacol Appl Skin Physiol. 2003 May-Jun;16(3):188-202. https://doi.org/10.1159/000069756

Linhares IM, Summers PR, Larsen B, Giraldo PC, Witkin SS. Contemporary perspectives on vaginal pH and lactobacilli. Am J Obstet Gynecol. 2011 Feb;204(2):120. e1–5. https://doi.org/10.1016/j.ajog.2010.07.010

Donders GGG, Grinceviciene S, Ruban K, Bellen G. Vaginal pH and microbiota during fluconazole maintenance treatment for recurrent vulvovaginal candidosis (RVVC). Diagn Microbiol Infect Dis. 2020 Jun;97(2):115024. https://doi.org/doi:10.1016/j.diagmicrobio.2020.115024

Alexiades MR. Fractional Co2 laser treatment of the vulva and vagina and the effect of postmenopausal duration on efficacy. Lasers Surg Med. 2021 Feb;53(2):185-98. https://doi.org/10.1002/lsm.23247

Carter J, Baser RE, Goldfrank DJ, Seidel B, Milli L, Stabile C, et al. A single-arm, prospective trial investigating the effectiveness of a non-hormonal vaginal moisturizer containing hyaluronic acid in postmenopausal cancer survivors. Support Care Cancer. 2021 Jan;29(1):311-22. https://doi.org/10.1007/s00520-020-05472-3

De Seta F, Caruso S, Di Lorenzo G, Romano F, Mirandola M, Nappi RE. Efficacy and safety of a new vaginal gel for the treatment of symptoms associated with vulvovaginal atrophy in postmenopausal women: a double-blind randomized placebo-controlled study. Maturitas. 2021 May;147:34-40. https://doi.org/10.1016/j.maturitas.2021.03.002

Melo MO, Campos PMBGM. Função de barreira da pele e pH cutâneo. Cosmetics & Toiletries. 2016 Mai-Jun;28:34-8.

Blaak J, Staib P. The relation of pH and skin cleansing. Curr Probl Dermatol. 2018;54:132-42. https://doi.org/10.1159/000489527

Lambers H, Piessens S, Bloem A, Pronk H, Finkel P. Natural skin surface pH is on average below 5, which is beneficial for its resident flora. Int J Cosmet Sci. 2006 Oct;28(5):359-70. https://doi.org/10.1111/j.1467-2494.2006.00344.x

Publicado

15/02/2024

Como Citar

1.
Urasaki MBM, Brandão E da S, Albuquerque RS de, Masson LM, Almeida J da S. O pH da região vulvar no ciclo vital: revisão de escopo. Rev. Eletr. Enferm. [Internet]. 15º de fevereiro de 2024 [citado 29º de maio de 2024];26:75717. Disponível em: https://revistas.ufg.br/fen/article/view/75717

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Artigo de Revisão