FTOX037 Cisplatin-induced DNA damage and neurotoxicity: Neuroprotection by coenzyme Q10

Authors

  • Carla da Silva Machado
  • Leonardo Meneghin Mendonça
  • Maria de Lourdes Pires Bianchi
  • Lusânia Maria Greggi Antunes

Abstract

Coenzyme Q10 (ubiquinone) is a liposoluble provitamin that is endogenously synthesized and naturally found in various foods items. It is predominantly located in the inner mitochondrial membrane, where it is involved in reactions necessary to carry out oxidative phosphorylation via the electron transport chain. Coenzyme Q10 has attracted attention for being a mitochondrial antioxidant, decreasing DNA damage and maintaining genome stability.

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Published

2012-12-27

How to Cite

MACHADO, C. da S.; MENDONÇA, L. M.; BIANCHI, M. de L. P.; ANTUNES, L. M. G. FTOX037 Cisplatin-induced DNA damage and neurotoxicity: Neuroprotection by coenzyme Q10. Revista Eletrônica de Farmácia, Goiânia, v. 9, n. 1, p. 1, 2012. Disponível em: https://revistas.ufg.br/REF/article/view/21886. Acesso em: 17 jul. 2024.

Issue

Section

Artigos Originais