BIO044 Chemoprotective action of L-Selenomethionine in HepG2 cells: evaluation of stress genes expression induced by H2O2.

Autores

  • Leonardo Campos Zanelatto
  • Lilian Areal Marques
  • Rafael Canfield Brianese
  • Catherine Kuhn Jacobs
  • Mário Sérgio Mantovani

Resumo

Among the agents that have been analyzed for chemoprotective potential for cancer, the components of diet have been the best scores, with the adequate intake of certain foods having the property to protect the DNA and consequently prevent the development of several cancers. Such studies provide evidence that foods provide nutrients and bioactive substances that can alter gene expression. The antioxidant activity of selenium appears to be responsible for its effectiveness in treating diseases which have as their development process the oxidative stress. Due to these aspects, it have been growing interest in investigating the roles of different selenium compounds as a therapeutic agent in various chronic degenerative diseases, such as cancers.

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Publicado

2012-12-27

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ZANELATTO, L. C.; MARQUES, L. A.; BRIANESE, R. C.; JACOBS, C. K.; MANTOVANI, M. S. BIO044 Chemoprotective action of L-Selenomethionine in HepG2 cells: evaluation of stress genes expression induced by H2O2. Revista Eletrônica de Farmácia, Goiânia, v. 9, n. 1, p. 1, 2012. Disponível em: https://revistas.ufg.br/REF/article/view/21916. Acesso em: 27 maio. 2022.

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