TFC029 Evaluation of emulsion solvent evaporation method as an approach to produce nanoparticles of Polycaprolactone containing ursolic acid

Autores

  • Juliana Palma Abriata Barcellos
  • Érika Cristina Vargas de Oliveira
  • Josimar de Oliveira Eloy
  • Mayara Garcia Trevisani
  • Juliana Maldonado Marchetti

Resumo

Preliminary studies have shown that ursolic acid (UA), a natural compound, presents important pharmacological properties, such as trypanocidal activity. However, it has low water solubility, which reduces its bioavailability. Among the existing drug delivery systems, polymeric nanoparticles (NPs) play a central role, due to their ability to sustain or control the release of drugs. Moreover, nanocoated systems are distinguished by high drug encapsulation efficiency, protection from degradation, and less likely to cause irritation due to their polymeric coating.

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Publicado

27-12-2012

Como Citar

Barcellos, J. P. A., de Oliveira, Érika C. V., Eloy, J. de O., Trevisani, M. G., & Marchetti, J. M. (2012). TFC029 Evaluation of emulsion solvent evaporation method as an approach to produce nanoparticles of Polycaprolactone containing ursolic acid. Revista Eletrônica De Farmácia, 9(1), 1. Recuperado de https://revistas.ufg.br/REF/article/view/21852

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