Neurotoxocariasis: a little-known manifestation of a neglected zoonosis

Autores

  • Pedro Paulo Chieffi Faculdade de Ciências Médicas da Santa Casa de São Paulo, Departamento de Ciências Patológicas, São Paulo, São Paulo, Brazil, pchieffi@usp.br https://orcid.org/0000-0003-0716-3032
  • Gabriela Rodrigues e Fonseca Faculdade de Ciências Médicas da Santa Casa de São Paulo, Departamento de Ciências Patológicas, São Paulo, São Paulo, Brazil, gabriela.rodrigues.fonseca@gmail.com https://orcid.org/0000-0001-6047-3668
  • Aline Diniz Cabral Faculdade de Ciências Médicas da Santa Casa de São Paulo, Departamento de Ciências Patológicas, São Paulo, São Paulo, Brazil, aline.cabral@fcmsantacasasp.edu.br https://orcid.org/0000-0002-9439-4463
  • Sergio Vieira dos Santos Faculdade de Ciências Médicas da Santa Casa de São Paulo, Departamento de Ciências Patológicas, São Paulo, São Paulo, Brazil, sergio.biol@hotmail.com https://orcid.org/0000-0002-2434-6909

DOI:

https://doi.org/10.5216/rpt.v53i4.80957

Resumo

This review covers general aspects of the occurrence of toxocariasis as a parasitic zoonosis, with a focus on neurotoxocariasis, a form of human infection that is still poorly understood and under-studied. The main aspects of manifestations resulting from the involvement of the central nervous system (CNS) in experimental animals and humans are discussed, with an emphasis on the difficulties in establishing a precise laboratory diagnosis of this infection, as well as the existing therapeutic challenges.

KEY WORDS: Neurotoxocariasis; toxocara canis; toxocara cati.

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Publicado

2025-01-29

Como Citar

CHIEFFI, P. P.; RODRIGUES E FONSECA, G.; DINIZ CABRAL, A.; VIEIRA DOS SANTOS, S. Neurotoxocariasis: a little-known manifestation of a neglected zoonosis. Revista de Patologia Tropical / Journal of Tropical Pathology, Goiânia, v. 53, n. 4, p. 267–276, 2025. DOI: 10.5216/rpt.v53i4.80957. Disponível em: https://revistas.ufg.br/iptsp/article/view/80957. Acesso em: 20 jun. 2025.

Edição

v. 53 n. 4 (2024)

Seção

REVISÃO / REVIEW

Licença

The manuscript submission must be accompanied by a letter signed by all authors stating their full name and email address, confirming that the manuscript or part of it has not been published or is under consideration for publication elsewhere, and agreeing to transfer copyright in all media and formats for Journal of Tropical Pathology.