Pulmonary mycobacteriosis: clinicalepidemiological profile of patients, treatment management, clinical outcome, and its species in the state of Mato Grosso, Brazil (2013-2020)

Autores

DOI:

https://doi.org/10.5216/rpt.v52i3.75557

Resumo

This study aimed to describe the clinical-epidemiological profile of patients in the State of Mato Grosso, who were affected by non-tuberculous mycobacteria (NTM), treatment management, clinical outcomes, and the species most commonly isolated from clinical samples. Between 2013 and 2020, the study analyzed 37 medical records from the Health Pulmonology sector of the Reference Center for Medium and High Complexity and it searched the Laboratory Environment Manager (GAL) system of the Central Public Health Laboratory of Mato Grosso. Patients with mycobacteriosis were predominantly diagnosed with MAC complex (avium-intracellulare complex) (n= 23.6%), with an average age of 62 years old; 51.4% were male, Caucasian (62%), and predominantly immunocompetent (HIV-negative). Most patients with comorbidities were older adults, they had sequelae of previous tuberculosis (56.8%), they were smokers (62.2%), and they had a low body mass index (29.7%) due to weight loss. Other patients had bronchiectasis (81.1%) and cavitary lesions (48.6%), with a lower incidence of chronic obstructive pulmonary disease (COPD). The municipalities with the highest rates of nontuberculous mycobacteria were Cuiabá (14 cases), Várzea Grande (five cases), Sinop (two cases), Nova Mutum (two cases), and Rondonópolis (two cases). This study presented data from the region, with a clinical, epidemiological profile, diversity of NTM species, and treatment management according to the patient’s response to the specific treatment of the identified Mycobacterium and various outcomes.

KEY WORDS: Non-tuberculous mycobacteria; MAC complex Mycobacterium; comorbidities; tuberculosis; mycobacteriosis.

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Biografia do Autor

Doracilde Terumi Takahara, Central Public Health Laboratory of the State of Mato Grosso, Department of Mycobacteriology, Cuiabá, MT, Brazil

and Federal University of Mato Grosso, Postgraduation Program in Health Science, Cuiabá, Mato Grosso, Brazil

Elaine Cristina de Oliveira, Central Public Health Laboratory of the State of Mato Grosso, Department of Mycobacteriology, Cuiabá, MT, Brazil

and Federal University of Mato Grosso, Postgraduation Program in Health Science, Cuiabá, Mato Grosso, Brazil

Hugo Dias Hoffmann-Santos, University Center of Varzea Grande, Department of Medicine, Várzea Grande, MT, Brazil

and Federal University of Mato Grosso, Postgraduation Program in Health Science, Cuiabá, Mato Grosso, Brazil

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Publicado

2023-10-06

Como Citar

TAKAHARA, D. T.; DE OLIVEIRA, E. C.; DIAS HOFFMANN-SANTOS, H. Pulmonary mycobacteriosis: clinicalepidemiological profile of patients, treatment management, clinical outcome, and its species in the state of Mato Grosso, Brazil (2013-2020). Revista de Patologia Tropical / Journal of Tropical Pathology, Goiânia, v. 52, n. 3, p. 199–213, 2023. DOI: 10.5216/rpt.v52i3.75557. Disponível em: https://revistas.ufg.br/iptsp/article/view/75557. Acesso em: 9 nov. 2024.

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Seção

ARTIGOS ORIGINAIS / ORIGINAL ARTICLES