PNS017 Enzyme inhibition in trypanosomatids: a therapeutic target for crude extracts and fractions of natural products

Autores

  • José Roberto de Sousa Filho
  • Marcos José Marques
  • Luis Vitor Silva do Sacramento
  • Diego Magno Assis
  • Thamyris Reis Moraes
  • Cláudia Quintino da Rocha
  • Alexandre Tourino Mendonça
  • Ivan de Oliveira Pereira

Resumo

Infections caused by trypanosomatids of Leishmania genus represent one of the largest global public health problems, currently with high endemicity especially in developing countries. The drugs of choice for the treatment of leishmaniasis are the pentavalent antimonials, which cause renal and cardiac toxicity, and induce resistance in the parasite.

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Publicado

2012-12-28

Como Citar

FILHO, J. R. de S.; MARQUES, M. J.; DO SACRAMENTO, L. V. S.; ASSIS, D. M.; MORAES, T. R.; DA ROCHA, C. Q.; MENDONÇA, A. T.; PEREIRA, I. de O. PNS017 Enzyme inhibition in trypanosomatids: a therapeutic target for crude extracts and fractions of natural products. Revista Eletrônica de Farmácia, Goiânia, v. 9, n. 1, p. 1, 2012. Disponível em: https://revistas.ufg.br/REF/article/view/21938. Acesso em: 28 mar. 2024.

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