PNS031 Topical f1-protein from latex Hevea brasiliensis accelerates wound healing in diabetes by enhancing insulin signaling

Autores

  • Thiago Antônio Moretti Andrade
  • Guilherme Ferreira Caetano
  • Camila Aparecida Pinheiro Landim
  • Marcel Nani Leite
  • Joaquim Coutinho Netto
  • Marco Andrey Cipriani Frade

Resumo

Insulin binds on its receptor and activates intracellular proteins like IRS, AKT, ERK, and SHC triggering metabolic and mitogenic effects. In diabetes, the reduced expression of these proteins is mainly related to insulin deficiency or resistance. Studies have confirmed clinical efficacy in wound healing by protein fraction F1 from natural latex of Hevea brasiliensis rubber tree, especially in wounds compromised by diabetes, which healing is impaired.

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Publicado

28-12-2012

Como Citar

Andrade, T. A. M., Caetano, G. F., Landim, C. A. P., Leite, M. N., Netto, J. C., & Frade, M. A. C. (2012). PNS031 Topical f1-protein from latex Hevea brasiliensis accelerates wound healing in diabetes by enhancing insulin signaling. Revista Eletrônica De Farmácia, 9(1), 1. Recuperado de https://revistas.ufg.br/REF/article/view/21942

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