FTOX045 Fractionation and functional characterization of Bothrops alternatus (Rhinocerophis alternatus) snake plasma: Evaluation of its inhibitory potential on proteolytic enzymes.

Autores

  • Tatiana Zapata Palacio
  • Norival Alves Santos-Filho
  • Adélia Cristina O. Cintra
  • Danilo L. Menaldo
  • Benedito Barraviera
  • Rui Seabra Ferreira Junior
  • Suely Vilela Sampaio

Resumo

Snake venoms are complex mixtures of toxins and enzymes showing several biological activities. They are rich in proteolitic enzymes (serine proteases and metalloproteases) involved in activities such as hemorrhage, coagulation disorders, necrosis and inflammation. The serum, plasma and/or muscles of snakes contain inhibitory compounds against these proteases as a protective mechanism avoiding possible damages caused by their own venoms. Preliminary results of this project showed several fractions obtained from snake plasma with high inhibitory potential on proteolytic enzymes.

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Publicado

27-12-2012

Como Citar

Palacio, T. Z., Santos-Filho, N. A., Cintra, A. C. O., Menaldo, D. L., Barraviera, B., Junior, R. S. F., & Sampaio, S. V. (2012). FTOX045 Fractionation and functional characterization of Bothrops alternatus (Rhinocerophis alternatus) snake plasma: Evaluation of its inhibitory potential on proteolytic enzymes. Revista Eletrônica De Farmácia, 9(1), 1. Recuperado de https://revistas.ufg.br/REF/article/view/21891

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