FTOX009 Effects of NO/cGMP inhibitors in a rat model of anaphylactic shock

Autores

  • Agnes Afrodite Sumarelli Albuquerque Fagundes
  • Marco Túlio Menezes Carvalho
  • Luciana Garros Ferreira
  • Ana Paula Cassiano Silveira
  • Verena Kise Capellini
  • Paulo Roberto Barbosa Evora
  • Andrea Carla Celotto

Resumo

Anaphylaxis has been defined as an acute syndrome, being the most severe clinical manifestation of allergic diseases. Many substances can mediate the anaphylactic shock. Among these substances, the histamine, the main secretory product of basophils and mast cells, induces nitric oxide (NO) release and the consequent cardiovascular manifestations observed in anaphylactic shock. The compound 48/80 (C48/80) can be used to induce anaphylactic shock since it promotes histamine release.

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Publicado

2012-12-27

Como Citar

FAGUNDES, A. A. S. A.; CARVALHO, M. T. M.; FERREIRA, L. G.; SILVEIRA, A. P. C.; CAPELLINI, V. K.; EVORA, P. R. B.; CELOTTO, A. C. FTOX009 Effects of NO/cGMP inhibitors in a rat model of anaphylactic shock. Revista Eletrônica de Farmácia, Goiânia, v. 9, n. 1, p. 1, 2012. Disponível em: https://revistas.ufg.br/REF/article/view/21877. Acesso em: 14 ago. 2022.

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